Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)
Public ClinicalTrials.gov record NCT04684524. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Double-blind Placebo-controlled Parallel Group Study Assessing the Efficacy and Safety of Dupilumab in Patients With Allergic Fungal Rhinosinusitis (AFRS)
Study identification
- NCT ID
- NCT04684524
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 62 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab SAR231893 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 6 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2020
- Primary completion
- Dec 13, 2024
- Completion
- Mar 6, 2025
- Last update posted
- Dec 21, 2025
2020 – 2025
United States locations
- U.S. sites
- 11
- U.S. states
- 8
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Asthma Allergy & Immunology Clinical Research Unit Site Number : 8400001 | Tampa | Florida | 33613 | — |
| Emory University Hospital Midtown Campus Site Number : 8400009 | Atlanta | Georgia | 30308 | — |
| Advanced ENT and Allergy Site Number : 8400004 | Louisville | Kentucky | 40220 | — |
| South Louisiana Ear, Nose, Throat and Facial Plastic Surgery Site Number : 8400019 | Mandeville | Louisiana | 70471 | — |
| National Allergy and Asthma Research, LLC Site Number : 8400002 | Charleston | South Carolina | 29407 | — |
| Vanderbilt University Medical Center Site Number : 8400013 | Nashville | Tennessee | 37232 | — |
| REX Clinical Trials Site Number : 8400017 | Beaumont | Texas | 77701-3713 | — |
| Ut- Houston Medical School Site Number : 8400010 | Houston | Texas | 77030 | — |
| USA Clinical Trials Site Number : 8400020 | San Antonio | Texas | 78229 | — |
| Alamo ENT Associates Site Number : 8400018 | San Antonio | Texas | 78258 | — |
| Eastern Virginia Medical School (EVMS) Medical Group - Otola Site Number : 8400008 | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04684524, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 21, 2025 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04684524 live on ClinicalTrials.gov.