Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema
Public ClinicalTrials.gov record NCT04697758. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 1/2a Study of the Safety and Bioactivity of AXT-107 in Subjects With Diabetic Macular Edema (DME)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is an open-label, dose-escalating, 48-week study assessing the safety, tolerability, bioactivity and duration of action of a single intravitreal injection of 0.1 mg, 0.25 mg, or 0.5 mg AXT107 in approximately 18 subjects (up to 6 subjects per dose) with Diabetic Macular Edema (DME).
Study identification
- NCT ID
- NCT04697758
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 6 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2020 (Actual)
- Primary completion
- Oct 1, 2022 (Actual)
- Completion
- Oct 1, 2022 (Actual)
- Last update posted
- Mar 22, 2024
2020 – 2022
United States locations
- U.S. sites
- 10
- U.S. states
- 8
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AsclepiX Investigative Site | Gilbert | Arizona | 85053 | — |
| AsclepiX Investigative Site | Los Angeles | California | 90211 | — |
| AsclepiX Investigative Site | St. Petersburg | Florida | 33711 | — |
| AsclepiX Investigative Site | Boston | Massachusetts | 02114 | — |
| AsclepiX Investigative Site | Reno | Nevada | 89502 | — |
| AsclepiX Investigative Site | Eugene | Oregon | 97401 | — |
| AsclepiX Investigative Site | Philadelphia | Pennsylvania | 19107 | — |
| AsclepiX Investigative Site | Abilene | Texas | 79606 | — |
| AsclepiX Investigative Site | McAllen | Texas | 78550 | — |
| AsclepiX Investigative Site | The Woodlands | Texas | 77384 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04697758, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 22, 2024 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04697758 live on ClinicalTrials.gov.