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Completed Phase 2 Interventional

A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

ClinicalTrials.gov ID: NCT04706923

Public ClinicalTrials.gov record NCT04706923. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 12:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase IIa, Open-label, Multiple Ascending Dose Confirmation Study of the Safety and Tolerability of Intravenous Administration of Brincidofovir in Subjects With Adenovirus Infection or Cytomegalovirus Infection

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the safety and tolerability of intravenous (IV) brincidofovir (BCV; SyB V-1901) 0.2 mg/kg, 0.3 mg/kg or 0.4 mg/kg dosed twice weekly (BIW) or 0.4 mg/kg dosed once weekly (QW) for 4 weeks in subjects with AdV, and IV BCV in subjects with CMV

Study identification

NCT ID
NCT04706923
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
SymBio Pharmaceuticals
Industry
Enrollment
53 participants

Conditions and interventions

Eligibility (public fields only)

Age range
2 Months and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 15, 2021
Primary completion
May 14, 2025
Completion
May 14, 2025
Last update posted
Aug 10, 2026

2021 – 2025

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
Research Site Los Angeles California 90027
Research Site Los Angeles California 90095
Research Site San Francisco California 94158
Research Site Chicago Illinois 60637
University of Nebraska Medical Center Omaha Nebraska 68198
Research Site Durham North Carolina 27710
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Research Site Philadelphia Pennsylvania 19104
St. Jude Children's Research Hospital Memphis Tennessee 38105
MD Anderson Cancer Center Houston Texas 77030
Research Site Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04706923, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 10, 2026 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04706923 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →