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Completed Phase 2 Interventional Results available

Non-proliferative Diabetic Retinopathy Treated With Runcaciguat

ClinicalTrials.gov ID: NCT04722991

Public ClinicalTrials.gov record NCT04722991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 12:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Placebo-controlled, Double-masked Proof-of-concept Study to Investigate the Efficacy and Safety of Runcaciguat (BAY 1101042) in Patients With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Study identification

NCT ID
NCT04722991
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Bayer
Industry
Enrollment
109 participants

Conditions and interventions

Interventions

  • Placebo Other
  • Runcaciguat (BAY1101042) Drug

Other · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 16, 2021
Primary completion
Mar 17, 2024
Completion
Apr 21, 2024
Last update posted
Apr 7, 2025

2021 – 2024

United States locations

U.S. sites
11
U.S. states
4
U.S. cities
9
Facility City State ZIP Site status
Retinal Consultants Medical Group, Inc Modesto California 95256
Florida Retina Consultants Lakeland Florida 33805
Eye Associates of Pinellas Pinellas Park Florida 33782
Cumberland Valley Retina Consultants | Hagerstown, MD Hagerstown Maryland 21740
Mid Atlantic Retina Specialists - Hagerstown Hagerstown Maryland 21740
Austin Research Center for Retina Austin Texas 78705-1023
Austin Retina Associates - Central Austin Texas 78705
Retinal Consultants of Texas - Bellaire Bellaire Texas 77401
Gulf Coast Eye Institute / Valley Retina Institute McAllen Texas 78503
Retinal Consultants of Texas - San Antonio San Antonio Texas 78240
Retina Consultants of Texas - The Woodlands The Woodlands Texas 77384

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04722991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 7, 2025 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04722991 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →