Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
Public ClinicalTrials.gov record NCT04725838. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The UPGRADE Study: Real World Outcomes® of Differential Target Multiplexed (DTM-SCS®) Stimulation in Existing and New Medtronic Implants
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM®) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celéri Health and is funded through a financial grant from Medtronic's External Research Program. The registry study will be conducted across approximately 25 centers in the United States with up to 600 participants enrolled.
Study identification
- NCT ID
- NCT04725838
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 255 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 29, 2021 (Actual)
- Primary completion
- Jul 1, 2023 (Actual)
- Completion
- Jul 1, 2023 (Actual)
- Last update posted
- Aug 21, 2024
2021 – 2023
United States locations
- U.S. sites
- 34
- U.S. states
- 15
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neuroversion | Anchorage | Alaska | 99508 | — |
| Desert Sky Spine & Sports Medicine | Oro Valley | Arizona | 85755 | — |
| Desert Sky Spine & Sports Medicine | Sierra Vista | Arizona | 85635 | — |
| NuVation Pain Group - Buena Park | Buena Park | California | 90621 | — |
| NuVation Pain Group - Los Angeles | Los Angeles | California | 90020 | — |
| Spine and Sports Specialty Medical Group | Orange | California | 92801 | — |
| Spine & Nerve Diagnostic Center - Roseville | Roseville | California | 95661 | — |
| Florida Pain Medicine - Brandon | Brandon | Florida | 33511 | — |
| Jax Spine & Pain Centers - Fleming Island | Fleming Island | Florida | 32003 | — |
| Jax Spine & Pain Centers - UF North | Jacksonville | Florida | 32218 | — |
| Jax Spine & Pain Centers - Jacksonville | Jacksonville | Florida | 32256 | — |
| Florida Spine & Pain Specialists | Riverview | Florida | 33569 | — |
| Jax Spine & Pain Centers -St. Augustine | Saint Augustine | Florida | 32080 | — |
| Florida Pain Medicine - Wesley Chapel | Wesley Chapel | Florida | 33544 | — |
| National Spine and Pain Centers - Winter Park, FL | Winter Park | Florida | 32789 | — |
| Centurion Spine & Pain Centers (Jax Spine) | Waycross | Georgia | 31501 | — |
| Millennium Pain Center (National Spine and Pain Centers - Bloomington, IL) | Bloomington | Illinois | 61704 | — |
| National Spine and Pain Centers - National Harbor (Oxon Hill) | Oxon Hill | Maryland | 20745 | — |
| National Spine and Pain Centers - Pikesville, MD | Pikesville | Maryland | 21208 | — |
| Comprehensive and Interventional Pain Management | Henderson | Nevada | 89052 | — |
| National Spine and Pain Centers - The Pain Management Center - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Carolinas Research Institute - Mallard Creek | Charlotte | North Carolina | 28262 | — |
| Carolinas Research Institute - Huntersville | Huntersville | North Carolina | 28078 | — |
| Premier Pain Treatment Institute - Hillsboro | Hillsboro | Ohio | 45133 | — |
| Premier Pain Treatment Institute - Loveland | Loveland | Ohio | 45140 | — |
| Premier Pain Treatment Institute - Mt. Orab | Mount Orab | Ohio | 45154 | — |
| Oklahoma Pain Physicians - Norman | Norman | Oklahoma | 73072 | — |
| Oklahoma Pain Physicians - Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Oklahoma Pain Physicians - Purcell | Purcell | Oklahoma | 73080 | — |
| North Texas Orthopedics & Spine Center- Keller/Alliance | Fort Worth | Texas | 76244 | — |
| North Texas Orthopedics & Spine Center - Grapevine | Grapevine | Texas | 76051 | — |
| Precision Spine Care | Tyler | Texas | 75701 | — |
| Valley Pain Consultants | Winchester | Virginia | 22601 | — |
| Northwest Pain Care | Spokane | Washington | 99201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04725838, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2024 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04725838 live on ClinicalTrials.gov.