ClinicalTrials.gov record
Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma
ClinicalTrials.gov ID: NCT04729959
Public ClinicalTrials.gov record NCT04729959. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 18, 2026, 3:38 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on the Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma
Study identification
- NCT ID
- NCT04729959
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 10, 2022
- Primary completion
- Jun 14, 2025
- Completion
- Sep 3, 2026
- Last update posted
- Mar 31, 2026
2022 – 2026
United States locations
- U.S. sites
- 95
- U.S. states
- 19
- U.S. cities
- 78
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente-Anaheim | Anaheim | California | 92806 | — |
| Kaiser Permanente-Bellflower | Bellflower | California | 90706 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Kaiser Permanente-Ontario | Ontario | California | 91761 | — |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | 92868 | — |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | 95661 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Kaiser Permanente-San Diego Zion | San Diego | California | 92120 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| UCHealth University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| UCHealth Memorial Hospital Central | Colorado Springs | Colorado | 80909 | — |
| Memorial Hospital North | Colorado Springs | Colorado | 80920 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| Cancer Care and Hematology-Fort Collins | Fort Collins | Colorado | 80528 | — |
| UCHealth Greeley Hospital | Greeley | Colorado | 80631 | — |
| Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | — |
| Miami Cancer Institute | Miami | Florida | 33176 | — |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| Rush MD Anderson Cancer Center | Chicago | Illinois | 60612 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | 60201 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| University of Kansas Cancer Center | Kansas City | Kansas | 66160 | — |
| University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | 66210 | — |
| University of Kansas Hospital-Indian Creek Campus | Overland Park | Kansas | 66211 | — |
| University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | 66205 | — |
| Ascension Via Christi Hospitals Wichita | Wichita | Kansas | 67214 | — |
| MaineHealth Maine Medical Center - Portland | Portland | Maine | 04102 | — |
| MaineHealth Cancer Care Center of York County | Sanford | Maine | 04073 | — |
| MaineHealth Maine Medical Center- Scarborough | Scarborough | Maine | 04074 | — |
| MaineHealth Cancer Care and IV Therapy - South Portland | South Portland | Maine | 04106 | — |
| UMass Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| University of Kansas Cancer Center - North | Kansas City | Missouri | 64154 | — |
| University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | 64064 | — |
| University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City | Missouri | 64116 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | — |
| Overlook Hospital | Summit | New Jersey | 07902 | — |
| NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Sanford Broadway Medical Center | Fargo | North Dakota | 58122 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| University of Cincinnati Cancer Center-West Chester | West Chester | Ohio | 45069 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Geisinger Medical Oncology-Lewisburg | Lewisburg | Pennsylvania | 17837 | — |
| University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| UPMC-Presbyterian Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Cancer Institute (UPCI) | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Shadyside Hospital | Pittsburgh | Pennsylvania | 15232 | — |
| Geisinger Cancer Services-Pottsville | Pottsville | Pennsylvania | 17901 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | 57104 | — |
| Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | 57117-5134 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04729959, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 31, 2026 · Synced May 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04729959 live on ClinicalTrials.gov.