Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye Disease
Public ClinicalTrials.gov record NCT04734210. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Masked, Dose-Ranging Study To Compare The Ocular Safety, Tolerability, And Efficacy Of SURF-200 Ophthalmic Solution (0.02% And 0.04% Betamethasone Sodium Phosphate) To Vehicle In Subjects With A Diagnosis Of Dry Eye Disease And Experiencing An Episodic Flare Up
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
SURF-200 is being studied in people experiencing an episodic flare-up of their dry eye disease. SURF-200 is an investigational drug (which means the study drug is currently being tested) in the form of a sterile eye drop. The purpose of this research study is to see how well SURF-200 works and what side effects there are, and to compare it with vehicle (placebo). The study will involve about 120 study participants at multiple research sites in the United States.
Study identification
- NCT ID
- NCT04734210
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 139 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 7, 2021 (Actual)
- Primary completion
- Oct 12, 2022 (Actual)
- Completion
- Oct 12, 2022 (Actual)
- Last update posted
- Jun 4, 2025
2021 – 2022
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Trinity Research Group | Dothan | Alabama | 36301 | — |
| Canyon City EyeCare | Azusa | California | 91702 | — |
| North Valley Eye Medical Group, Inc. | Mission Hills | California | 91345 | — |
| LoBue Laser and Eye Medical Center | Murrieta | California | 92562 | — |
| Visionary Eye Institute | Newport Beach | California | 92663 | — |
| North Bay Eye Associates | Petaluma | California | 94954 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Vision Institute | Colorado Springs | Colorado | 80907 | — |
| The Eye Center of Northern Colorado | Fort Collins | Colorado | 80528 | — |
| Connecticut Eye Consultants, PC | Danbury | Connecticut | 06810 | — |
| The Eye Associates of Manatee | Bradenton | Florida | 34209 | — |
| Blue Ocean Clinical Research (The Macula Center) | Clearwater | Florida | 33761 | — |
| Eye Associates of Fort Myers | Fort Myers | Florida | 33901 | — |
| Eye Center of North Florida PA | Panama City | Florida | 32405 | — |
| Coastal Research Associates, LLC | Roswell | Georgia | 30076 | — |
| Cincinnati Eye Institute | Edgewood | Kentucky | 41017 | — |
| Kentucky Eye Institute | Lexington | Kentucky | 40517 | — |
| Chu Vision Institute | Bloomington | Minnesota | 55420 | — |
| Complete Eye Care | Hamel | Minnesota | 55340 | — |
| Tauber Eye Center | Kansas City | Missouri | 64111 | — |
| Ophthalmology Consultants Ltd. | St Louis | Missouri | 63131 | — |
| Alterman, Modi & Wolter | Poughkeepsie | New York | 12603 | — |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | — |
| Bucci Laser Vision | Wilkes-Barre | Pennsylvania | 18702 | — |
| Total Eye Care, PA | Memphis | Tennessee | 38119 | — |
| West TN EyeCare dba Toyos Clinic | Nashville | Tennessee | 37215 | — |
| Advanced Laser Vision & Surgical Institute | Houston | Texas | 77034 | — |
| R and R Eye Research, LLC | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04734210, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2025 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04734210 live on ClinicalTrials.gov.