ClinicalTrials.gov record
Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents
ClinicalTrials.gov ID: NCT04739800
Public ClinicalTrials.gov record NCT04739800. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Trial of Triplet Therapy (A PD-L1 Inhibitor Durvalumab (MEDI4736) in Combination With Olaparib and Cediranib) Compared to Olaparib and Cediranib or Durvalumab (MEDI4736) and Cediranib or Standard of Care Chemotherapy in Women With Platinum-Resistant Recurrent Epithelial Ovarian Cancer, Primary Peritoneal or Fallopian Cancer Who Have Received Prior Bevacizumab
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial studies the possible benefits of treatment with different combinations of the drugs durvalumab, olaparib and cediranib vs. the usual treatment in patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back after a period of improvement with platinum therapy (recurrent platinum resistant). Usual treatment is the type of treatment most patients with this condition receive if they are not part of a clinical study. Combination therapies studied in this trial include MEDI4736 (durvalumab) plus olaparib and cediranib, durvalumab and cediranib, or olaparib and cediranib. Monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumors cells to grow and spread. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep cancer cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. Cediranib may stop the growth of tumor cells by blocking VEGF (an enzyme). needed for cell growth. Giving different combinations of durvalumab, olaparib and cediranib may work better in increasing the duration of time that the cancer does not progress compared to the usual treatment.
Study identification
- NCT ID
- NCT04739800
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 120 participants
Conditions and interventions
Conditions
- Fallopian Tube Mucinous Adenocarcinoma
- Ovarian Seromucinous Carcinoma
- Platinum-Refractory Fallopian Tube Carcinoma
- Platinum-Refractory Ovarian Carcinoma
- Platinum-Refractory Primary Peritoneal Carcinoma
- Recurrent Fallopian Tube Clear Cell Adenocarcinoma
- Recurrent Fallopian Tube Endometrioid Adenocarcinoma
- Recurrent Fallopian Tube High Grade Serous Adenocarcinoma
- Recurrent Fallopian Tube Mucinous Adenocarcinoma
- Recurrent Fallopian Tube Transitional Cell Carcinoma
- Recurrent Fallopian Tube Undifferentiated Carcinoma
- Recurrent Low Grade Fallopian Tube Serous Adenocarcinoma
- Recurrent Ovarian Clear Cell Adenocarcinoma
- Recurrent Ovarian Endometrioid Adenocarcinoma
- Recurrent Ovarian High Grade Serous Adenocarcinoma
- Recurrent Ovarian Low Grade Serous Adenocarcinoma
- Recurrent Ovarian Mucinous Adenocarcinoma
- Recurrent Ovarian Seromucinous Carcinoma
- Recurrent Ovarian Transitional Cell Carcinoma
- Recurrent Ovarian Undifferentiated Carcinoma
- Recurrent Platinum-Resistant Fallopian Tube Carcinoma
- Recurrent Platinum-Resistant Ovarian Carcinoma
- Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
- Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
- Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
- Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma
- Recurrent Primary Peritoneal Low Grade Serous Adenocarcinoma
- Recurrent Primary Peritoneal Transitional Cell Carcinoma
- Recurrent Primary Peritoneal Undifferentiated Carcinoma
- Refractory Fallopian Tube Clear Cell Adenocarcinoma
- Refractory Fallopian Tube Endometrioid Adenocarcinoma
- Refractory Fallopian Tube High Grade Serous Adenocarcinoma
- Refractory Fallopian Tube Mucinous Adenocarcinoma
- Refractory Fallopian Tube Transitional Cell Carcinoma
- Refractory Fallopian Tube Undifferentiated Carcinoma
- Refractory Low Grade Fallopian Tube Serous Adenocarcinoma
- Refractory Ovarian Clear Cell Adenocarcinoma
- Refractory Ovarian Endometrioid Adenocarcinoma
- Refractory Ovarian High Grade Serous Adenocarcinoma
- Refractory Ovarian Low Grade Serous Adenocarcinoma
- Refractory Ovarian Mucinous Adenocarcinoma
- Refractory Ovarian Seromucinous Carcinoma
- Refractory Ovarian Transitional Cell Carcinoma
- Refractory Ovarian Undifferentiated Carcinoma
- Refractory Primary Peritoneal Clear Cell Adenocarcinoma
- Refractory Primary Peritoneal Endometrioid Adenocarcinoma
- Refractory Primary Peritoneal High Grade Serous Adenocarcinoma
- Refractory Primary Peritoneal Low Grade Serous Adenocarcinoma
- Refractory Primary Peritoneal Transitional Cell Carcinoma
- Refractory Primary Peritoneal Undifferentiated Carcinoma
Interventions
- Biospecimen Collection Procedure
- Cediranib Maleate Drug
- Computed Tomography Procedure
- Computed Tomography with Contrast Procedure
- Durvalumab Biological
- Echocardiography Test Procedure
- Magnetic Resonance Imaging Procedure
- Multigated Acquisition Scan Procedure
- Olaparib Drug
- Paclitaxel Drug
- Pegylated Liposomal Doxorubicin Hydrochloride Drug
- Topotecan Hydrochloride Drug
Procedure · Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 10, 2021 (Actual)
- Primary completion
- Jan 26, 2023 (Actual)
- Completion
- Jun 25, 2027 (Estimated)
- Last update posted
- Oct 1, 2026
2021 – 2027
United States locations
- U.S. sites
- 384
- U.S. states
- 42
- U.S. cities
- 291
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anchorage Associates in Radiation Medicine | Anchorage | Alaska | 98508 | — |
| Anchorage Radiation Therapy Center | Anchorage | Alaska | 99504 | — |
| Alaska Breast Care and Surgery LLC | Anchorage | Alaska | 99508 | — |
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Alaska Women's Cancer Care | Anchorage | Alaska | 99508 | — |
| Anchorage Oncology Centre | Anchorage | Alaska | 99508 | — |
| Katmai Oncology Group | Anchorage | Alaska | 99508 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Fairbanks Memorial Hospital | Fairbanks | Alaska | 99701 | — |
| CTCA at Western Regional Medical Center | Goodyear | Arizona | 85338 | — |
| Cancer Center at Saint Joseph's | Phoenix | Arizona | 85004 | — |
| Mercy Hospital Fort Smith | Fort Smith | Arkansas | 72903 | — |
| CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | 71913 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande | California | 93420 | — |
| Sutter Auburn Faith Hospital | Auburn | California | 95602 | — |
| Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | 95603 | — |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | 94704 | — |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | 95682 | — |
| Eden Hospital Medical Center | Castro Valley | California | 94546 | — |
| John Muir Medical Center-Concord | Concord | California | 94520 | — |
| Sutter Davis Hospital | Davis | California | 95616 | — |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | — |
| Palo Alto Medical Foundation-Fremont | Fremont | California | 94538 | — |
| City of Hope Antelope Valley | Lancaster | California | 93534 | — |
| Los Angeles General Medical Center | Los Angeles | California | 90033 | — |
| USC / Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Memorial Medical Center | Modesto | California | 95355 | — |
| Palo Alto Medical Foundation-Camino Division | Mountain View | California | 94040 | — |
| Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California | 94040 | — |
| Palo Alto Medical Foundation Health Care | Palo Alto | California | 94301 | — |
| Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | 95661 | — |
| Sutter Roseville Medical Center | Roseville | California | 95661 | — |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | — |
| California Pacific Medical Center-Pacific Campus | San Francisco | California | 94115 | — |
| Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | 93401 | — |
| Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California | 95065 | — |
| Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | 93444 | — |
| Sutter Pacific Medical Foundation | Santa Rosa | California | 95403 | — |
| City of Hope South Pasadena | South Pasadena | California | 91030 | — |
| Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | 94086 | — |
| City of Hope Upland | Upland | California | 91786 | — |
| Sutter Solano Medical Center/Cancer Center | Vallejo | California | 94589 | — |
| John Muir Medical Center-Walnut Creek | Walnut Creek | California | 94598 | — |
| Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | 80012 | — |
| Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | 80304 | — |
| Rocky Mountain Cancer Centers - Centennial | Centennial | Colorado | 80112 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | 80907 | — |
| AdventHealth Porter | Denver | Colorado | 80210 | — |
| CommonSpirit Cancer Center Mercy | Durango | Colorado | 81301 | — |
| Mercy Medical Center | Durango | Colorado | 81301 | — |
| CommonSpirit Saint Anthony Hospital Cancer Center | Lakewood | Colorado | 80228 | — |
| Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | 80120 | — |
| AdventHealth Littleton | Littleton | Colorado | 80122 | — |
| Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | 80124 | — |
| Longmont United Hospital | Longmont | Colorado | 80501 | — |
| Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | 80501 | — |
| Banner North Colorado Medical Center - Loveland Campus | Loveland | Colorado | 80539 | — |
| AdventHealth Parker | Parker | Colorado | 80138 | — |
| Saint Mary Corwin Medical Center | Pueblo | Colorado | 81004 | — |
| Danbury Hospital | Danbury | Connecticut | 06810 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| Northside Hospital | Atlanta | Georgia | 30342 | — |
| CTCA at Southeastern Regional Medical Center | Newnan | Georgia | 30265 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | 96826 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Saint Luke's Cancer Institute - Boise | Boise | Idaho | 83712 | — |
| Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | 83605 | — |
| Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | 83814 | — |
| Walter Knox Memorial Hospital | Emmett | Idaho | 83617 | — |
| Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | 83619 | — |
| Idaho Urologic Institute-Meridian | Meridian | Idaho | 83642 | — |
| Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | 83642 | — |
| Saint Alphonsus Cancer Care Center-Nampa | Nampa | Idaho | 83687 | — |
| Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | 83687 | — |
| Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | 83854 | — |
| Kootenai Clinic Cancer Services - Sandpoint | Sandpoint | Idaho | 83864 | — |
| Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | 83301 | — |
| OSF Saint Anthony's Health Center | Alton | Illinois | 62002 | — |
| Rush-Copley Medical Center | Aurora | Illinois | 60504 | — |
| Illinois CancerCare-Bloomington | Bloomington | Illinois | 61704 | — |
| Illinois CancerCare-Canton | Canton | Illinois | 61520 | — |
| Memorial Hospital of Carbondale | Carbondale | Illinois | 62902 | — |
| SIH Cancer Institute | Carterville | Illinois | 62918 | — |
| Illinois CancerCare-Carthage | Carthage | Illinois | 62321 | — |
| Centralia Oncology Clinic | Centralia | Illinois | 62801 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Rush MD Anderson Cancer Center | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Carle at The Riverfront | Danville | Illinois | 61832 | — |
| Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | 62526 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Illinois CancerCare-Dixon | Dixon | Illinois | 61021 | — |
| Carle Physician Group-Effingham | Effingham | Illinois | 62401 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| Illinois CancerCare-Eureka | Eureka | Illinois | 61530 | — |
| NorthShore University HealthSystem-Evanston Hospital | Evanston | Illinois | 60201 | — |
| Illinois CancerCare-Galesburg | Galesburg | Illinois | 61401 | — |
| Western Illinois Cancer Treatment Center | Galesburg | Illinois | 61401 | — |
| Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | 60134 | — |
| NorthShore University HealthSystem-Glenbrook Hospital | Glenview | Illinois | 60026 | — |
| Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| NorthShore University HealthSystem-Highland Park Hospital | Highland Park | Illinois | 60035 | — |
| Sudarshan K Sharma MD Limited-Gynecologic Oncology | Hinsdale | Illinois | 60521 | — |
| Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | 61443 | — |
| Illinois CancerCare-Macomb | Macomb | Illinois | 61455 | — |
| Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | 61938 | — |
| SSM Health Good Samaritan | Mount Vernon | Illinois | 62864 | — |
| UC Comprehensive Cancer Center at Silver Cross | New Lenox | Illinois | 60451 | — |
| Cancer Care Center of O'Fallon | O'Fallon | Illinois | 62269 | — |
| University of Chicago Medicine-Orland Park | Orland Park | Illinois | 60462 | — |
| Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | 61350 | — |
| Illinois CancerCare-Pekin | Pekin | Illinois | 61554 | — |
| Illinois CancerCare-Peoria | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| Illinois CancerCare-Peru | Peru | Illinois | 61354 | — |
| Valley Radiation Oncology | Peru | Illinois | 61354 | — |
| Illinois CancerCare-Princeton | Princeton | Illinois | 61356 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Springfield Clinic | Springfield | Illinois | 62702 | — |
| Springfield Memorial Hospital | Springfield | Illinois | 62781 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| The Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | — |
| Illinois CancerCare - Washington | Washington | Illinois | 61571 | — |
| Rush-Copley Healthcare Center | Yorkville | Illinois | 60560 | — |
| Midwestern Regional Medical Center | Zion | Illinois | 60099 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Mary Greeley Medical Center | Ames | Iowa | 50010 | — |
| McFarland Clinic - Ames | Ames | Iowa | 50010 | — |
| McFarland Clinic - Boone | Boone | Iowa | 50036 | — |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | — |
| Oncology Associates at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Mercy Cancer Center-West Lakes | Clive | Iowa | 50325 | — |
| UI Health Care Mission Cancer and Blood - West Des Moines Clinic | Clive | Iowa | 50325 | — |
| Alegent Health Mercy Hospital | Council Bluffs | Iowa | 51503 | — |
| Greater Regional Medical Center | Creston | Iowa | 50801 | — |
| Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| UI Health Care Mission Cancer and Blood - Laurel Clinic | Des Moines | Iowa | 50314 | — |
| McFarland Clinic - Trinity Cancer Center | Fort Dodge | Iowa | 50501 | — |
| University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | 52242 | — |
| McFarland Clinic - Jefferson | Jefferson | Iowa | 50129 | — |
| McFarland Clinic - Marshalltown | Marshalltown | Iowa | 50158 | — |
| Mercy Medical Center-West Lakes | West Des Moines | Iowa | 50266 | — |
| Central Care Cancer Center - Garden City | Garden City | Kansas | 67846 | — |
| Central Care Cancer Center - Great Bend | Great Bend | Kansas | 67530 | — |
| CommonSpirit Saint Joseph Hospital - Bardstown | Bardstown | Kentucky | 40004 | — |
| Commonwealth Cancer Center-Corbin | Corbin | Kentucky | 40701 | — |
| Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | 40504 | — |
| CommonSpirit Saint Joseph Medical Center - East Lexington | Lexington | Kentucky | 40509 | — |
| CommonSpirit Saint Joseph Hospital London | London | Kentucky | 40741 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| Saints Mary and Elizabeth Hospital | Louisville | Kentucky | 40215 | — |
| UofL Health Medical Center Northeast | Louisville | Kentucky | 40245 | — |
| Jewish Hospital Medical Center South | Shepherdsville | Kentucky | 40165 | — |
| Our Lady of the Lake Medical Oncology | Baton Rouge | Louisiana | 70817 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Lafayette Family Cancer Center-EMMC | Brewer | Maine | 04412 | — |
| MaineHealth Maine Medical Center- Scarborough | Scarborough | Maine | 04074 | — |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | — |
| National Institutes of Health Clinical Center | Bethesda | Maryland | 20892 | — |
| University of Michigan Rogel Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Corewell Health Dearborn Hospital | Dearborn | Michigan | 48124 | — |
| Corewell Health William Beaumont University Hospital | Royal Oak | Michigan | 48073 | — |
| Corewell Health Beaumont Troy Hospital | Troy | Michigan | 48085 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Minnesota Oncology - Burnsville | Burnsville | Minnesota | 55337 | — |
| Cambridge Medical Center | Cambridge | Minnesota | 55008 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | 55369 | — |
| Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | 55109 | — |
| Saint John's Hospital - Healtheast | Maplewood | Minnesota | 55109 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Health Partners Inc | Minneapolis | Minnesota | 55454 | — |
| University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | 55455 | — |
| Monticello Cancer Center | Monticello | Minnesota | 55362 | — |
| New Ulm Medical Center | New Ulm | Minnesota | 56073 | — |
| Fairview Northland Medical Center | Princeton | Minnesota | 55371 | — |
| North Memorial Medical Health Center | Robbinsdale | Minnesota | 55422 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Saint Francis Regional Medical Center | Shakopee | Minnesota | 55379 | — |
| Lakeview Hospital | Stillwater | Minnesota | 55082 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | 55125 | — |
| Fairview Lakes Medical Center | Wyoming | Minnesota | 55092 | — |
| Mercy Oncology and Hematology - Clayton-Clarkson | Ballwin | Missouri | 63011 | — |
| Central Care Cancer Center - Bolivar | Bolivar | Missouri | 65613 | — |
| Mercy Cancer Center - Cape Girardeau | Cape Girardeau | Missouri | 63703 | — |
| Saint Francis Medical Center | Cape Girardeau | Missouri | 63703 | — |
| Parkland Health Center - Farmington | Farmington | Missouri | 63640 | — |
| MU Health Care Goldschmidt Cancer Center | Jefferson City | Missouri | 65109 | — |
| Freeman Health System | Joplin | Missouri | 64804 | — |
| Mercy Hospital Joplin | Joplin | Missouri | 64804 | — |
| Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | 65401 | — |
| Phelps Health Delbert Day Cancer Institute | Rolla | Missouri | 65401 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | 63670 | — |
| Mercy Hospital Springfield | Springfield | Missouri | 65804 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Mercy Infusion Center - Chippewa | St Louis | Missouri | 63109 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Mercy Hospital South | St Louis | Missouri | 63128 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Missouri Baptist Sullivan Hospital | Sullivan | Missouri | 63080 | — |
| Mercy Hospital Washington | Washington | Missouri | 63090 | — |
| Community Hospital of Anaconda | Anaconda | Montana | 59711 | — |
| Billings Clinic Cancer Center | Billings | Montana | 59101 | — |
| Bozeman Health Deaconess Hospital | Bozeman | Montana | 59715 | — |
| Benefis Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Great Falls Clinic | Great Falls | Montana | 59405 | — |
| Logan Health Medical Center | Kalispell | Montana | 59901 | — |
| Saint Patrick Hospital - Community Hospital | Missoula | Montana | 59802 | — |
| Community Medical Center | Missoula | Montana | 59804 | — |
| Nebraska Cancer Specialists/Oncology Hematology West PC | Grand Island | Nebraska | 68803 | — |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | — |
| Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | 68510 | — |
| Cancer Partners of Nebraska | Lincoln | Nebraska | 68516 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Alegent Health Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Alegent Health Lakeside Hospital | Omaha | Nebraska | 68130 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Midlands Community Hospital | Papillion | Nebraska | 68046 | — |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89106 | — |
| Jersey Shore Medical Center | Neptune City | New Jersey | 07753 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Memorial Medical Center-Las Cruces | Las Cruces | New Mexico | 88011 | — |
| Presbyterian Rust Medical Center/Jorgensen Cancer Center | Rio Rancho | New Mexico | 87124 | — |
| Northwell Health Imbert Cancer Center | Bay Shore | New York | 11706 | — |
| Island Gynecologic Oncology | Brightwaters | New York | 11718 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Northwell Health/Center for Advanced Medicine | Lake Success | New York | 11042 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Dickstein Cancer Treatment Center | White Plains | New York | 10601 | — |
| Southeastern Medical Oncology Center-Clinton | Clinton | North Carolina | 28328 | — |
| Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | 27534 | — |
| Southeastern Medical Oncology Center-Jacksonville | Jacksonville | North Carolina | 28546 | — |
| Summa Health System - Akron Campus | Akron | Ohio | 44304 | — |
| Aultman Alliance Community Hospital | Alliance | Ohio | 44601 | — |
| UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio | 44122 | — |
| Strecker Cancer Center-Belpre | Belpre | Ohio | 45714 | — |
| Aultman Health Foundation | Canton | Ohio | 44710 | — |
| Miami Valley Hospital South | Centerville | Ohio | 45459 | — |
| Geauga Hospital | Chardon | Ohio | 44024 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | 45220 | — |
| Bethesda North Hospital | Cincinnati | Ohio | 45242 | — |
| TriHealth Cancer Institute-Westside | Cincinnati | Ohio | 45247 | — |
| TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | 45255 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Mount Carmel East Hospital | Columbus | Ohio | 43213 | — |
| Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | 43214 | — |
| Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Grant Medical Center | Columbus | Ohio | 43215 | — |
| The Mark H Zangmeister Center | Columbus | Ohio | 43219 | — |
| Mount Carmel Health Center West | Columbus | Ohio | 43222 | — |
| Doctors Hospital | Columbus | Ohio | 43228 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Delaware Health Center-Grady Cancer Center | Delaware | Ohio | 43015 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Dublin Methodist Hospital | Dublin | Ohio | 43016 | — |
| Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio | 43230 | — |
| Mount Carmel Grove City Hospital | Grove City | Ohio | 43123 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Saint Rita's Medical Center | Lima | Ohio | 45801 | — |
| OhioHealth Mansfield Hospital | Mansfield | Ohio | 44903 | — |
| Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| OhioHealth Marion General Hospital | Marion | Ohio | 43302 | — |
| Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | 44124 | — |
| UH Seidman Cancer Center at Lake Health Mentor Campus | Mentor | Ohio | 44060 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Newark Radiation Oncology | Newark | Ohio | 43055 | — |
| Mercy Health - Perrysburg Hospital | Perrysburg | Ohio | 43551 | — |
| Southern Ohio Medical Center | Portsmouth | Ohio | 45662 | — |
| Mercy Health - Saint Vincent Hospital | Toledo | Ohio | 43608 | — |
| Mercy Health - Saint Anne Hospital | Toledo | Ohio | 43623 | — |
| University Hospitals Sharon Health Center | Wadsworth | Ohio | 44281 | — |
| Saint Ann's Hospital | Westerville | Ohio | 43081 | — |
| UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio | 44145 | — |
| Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | 43701 | — |
| Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | 73505 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | 74146 | — |
| Saint Alphonsus Cancer Care Center-Baker City | Baker City | Oregon | 97814 | — |
| Saint Charles Health System | Bend | Oregon | 97701 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | 97015 | — |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | — |
| Providence Newberg Medical Center | Newberg | Oregon | 97132 | — |
| Saint Alphonsus Cancer Care Center-Ontario | Ontario | Oregon | 97914 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Saint Charles Health System-Redmond | Redmond | Oregon | 97756 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| UPMC Hillman Cancer Center at Butler Health System | Butler | Pennsylvania | 16001 | — |
| UPMC Hillman Cancer Center Erie | Erie | Pennsylvania | 16505 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Jefferson Torresdale Hospital | Philadelphia | Pennsylvania | 19114 | — |
| UPMC-Magee Womens Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | — |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | — |
| UPMC-Passavant Hospital | Pittsburgh | Pennsylvania | 15237 | — |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Women and Infants Hospital | Providence | Rhode Island | 02905 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Saint Francis Hospital | Greenville | South Carolina | 29601 | — |
| Saint Francis Cancer Center | Greenville | South Carolina | 29607 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Bristol Regional Medical Center | Bristol | Tennessee | 37620 | — |
| Ballad Health Cancer Care - Kingsport | Kingsport | Tennessee | 37660 | — |
| Wellmont Holston Valley Hospital and Medical Center | Kingsport | Tennessee | 37660 | — |
| Covenant Health Cancer Centers | Knoxville | Tennessee | 37916 | — |
| Covenant Health Cancer Centers - West | Knoxville | Tennessee | 37932 | — |
| Vanderbilt Breast Center at One Hundred Oaks | Nashville | Tennessee | 37204 | — |
| Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Saint Joseph Regional Cancer Center | Bryan | Texas | 77802 | — |
| Parkland Memorial Hospital | Dallas | Texas | 75235 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Methodist Willowbrook Hospital | Houston | Texas | 77070 | — |
| Houston Methodist West Hospital | Houston | Texas | 77094 | — |
| Houston Methodist Sugar Land Hospital | Sugar Land | Texas | 77479 | — |
| Houston Methodist The Woodlands Hospital | The Woodlands | Texas | 77385 | — |
| Ballad Health Cancer Care - Bristol | Bristol | Virginia | 24201 | — |
| Ballad Health Cancer Care - Norton | Norton | Virginia | 24273 | — |
| Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | 98520 | — |
| PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Highline Medical Center-Main Campus | Burien | Washington | 98166 | — |
| Providence Regional Cancer System-Centralia | Centralia | Washington | 98531 | — |
| Swedish Cancer Institute-Edmonds | Edmonds | Washington | 98026 | — |
| Saint Elizabeth Hospital | Enumclaw | Washington | 98022 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Saint Francis Hospital | Federal Way | Washington | 98003 | — |
| Swedish Cancer Institute-Issaquah | Issaquah | Washington | 98029 | — |
| Kadlec Clinic Hematology and Oncology | Kennewick | Washington | 99336 | — |
| Providence Regional Cancer System-Lacey | Lacey | Washington | 98503 | — |
| Saint Clare Hospital | Lakewood | Washington | 98499 | — |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | — |
| Jefferson Healthcare | Port Townsend | Washington | 98368 | — |
| Pacific Gynecology Specialists | Seattle | Washington | 98104 | — |
| Swedish Medical Center-Ballard Campus | Seattle | Washington | 98107 | — |
| Swedish Medical Center-Cherry Hill | Seattle | Washington | 98122-5711 | — |
| Swedish Medical Center-First Hill | Seattle | Washington | 98122 | — |
| PeaceHealth United General Medical Center | Sedro-Woolley | Washington | 98284 | — |
| Providence Regional Cancer System-Shelton | Shelton | Washington | 98584 | — |
| Saint Joseph Medical Center Hematology and Oncology - Silverdale | Silverdale | Washington | 98383 | — |
| Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington | 98405 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| Legacy Salmon Creek Hospital | Vancouver | Washington | 98686 | — |
| Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | 99362 | — |
| Providence Regional Cancer System-Yelm | Yelm | Washington | 98597 | — |
| Vandalia Health/CAMC Institute for Academic Medicine | Charleston | West Virginia | 25304 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| ProHealth D N Greenwald Center | Mukwonago | Wisconsin | 53149 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | 53066 | — |
| Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235-1495 | — |
| ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
| UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | 53188 | — |
| Billings Clinic-Cody | Cody | Wyoming | 82414 | — |
| Welch Cancer Center | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04739800, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 1, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04739800 live on ClinicalTrials.gov.