Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)
Public ClinicalTrials.gov record NCT04745351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Study Evaluating the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate whether remdesivir (RDV, GS-5734™) reduces the composite risk of death or invasive mechanical ventilation (IMV) through Day 29 in participants with severely reduced kidney function who are hospitalized for coronavirus disease 2019 (COVID-19).
Study identification
- NCT ID
- NCT04745351
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 249 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2021 (Actual)
- Primary completion
- Apr 20, 2022 (Actual)
- Completion
- May 24, 2022 (Actual)
- Last update posted
- May 12, 2023
2021 – 2022
United States locations
- U.S. sites
- 41
- U.S. states
- 20
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Vincent's Health System | Birmingham | Alabama | 35205 | — |
| UAB Hospital | Birmingham | Alabama | 35294 | — |
| Pulmonary Associates of Mobile, P.C. | Mobile | Alabama | 36608 | — |
| St. Joseph Hospital Eureka | Eureka | California | 95501 | — |
| Hoag Memorial Hospital Presbyterian, 16200 Sand Canyon Ave | Irvine | California | 92618 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | — |
| Sutter Medical Center Sacramento | Sacramento | California | 95816 | — |
| Torrance Memorial Medical Center | Torrance | California | 90505 | — |
| MedStar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| George Washington Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| North Florida/ South Georgia Veterans Health System | Gainesville | Florida | 32608 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| Genesis Clinical Research | Tampa | Florida | 33603 | — |
| Northwestern Medicine Central DuPage Hospital | Winfield | Illinois | 60190 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Tulane Medical Center, 2000 Canal St. | New Orleans | Louisiana | 70112 | — |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | — |
| Wake Forest University Health Sciences | Bethesda | Maryland | 20892 | — |
| Holy Cross Hospital, 19801 Observation Dr | Germantown | Maryland | 20876 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Newton-Wellesley Hospital | Newton | Massachusetts | 02462 | — |
| St. Clair Nephrology Research | Grosse Pointe Woods | Michigan | 48236 | — |
| G.V. (Sonny) Montgomery VAMC | Jackson | Michigan | 39216 | — |
| Mayo Clinic Hospital | Rochester | Minnesota | 55902 | — |
| Saint Michael's Medical Center | Newark | New Jersey | 07102 | — |
| University of New Mexico Hospital | Albuquerque | New Mexico | 87131 | — |
| New York - Presbyterian Hospital/Weill Cornell Medical Center | New York | New York | 10065 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11716 | — |
| Jacobi Medical Center | The Bronx | New York | 10461 | — |
| PMG Infectious Disease Consultants (administrative) | Portland | Oregon | 92775 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Medical University of South Carolina | Charleston | South Carolina | 92037 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Memorial Hermann Hospital at TMC | Houston | Texas | 77030 | — |
| VCU Health Medical Center | Richmond | Virginia | 23298 | — |
| Providence Regional Medical Center Everett | Everett | Washington | 98201 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| Providence Health Care | Spokane | Washington | 99204 | — |
| Providence Health Care, 5633 N Lidgerwood | Spokane | Washington | 99208 | — |
| MultiCare Good Samaritan Hospital | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04745351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 12, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04745351 live on ClinicalTrials.gov.