Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation
Public ClinicalTrials.gov record NCT04755283. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, RandomiZed, Active-ControLled Study to Evaluate the Safety and Tolerability of Two Blinded Doses of Abelacimab (MAA868) Compared With Open-Label Rivaroxaban in Patients With Atrial Fibrillation (AZALEA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the ANT-006 study is to evaluate the bleeding profile of abelacimab relative to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.
Study identification
- NCT ID
- NCT04755283
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,287 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2, 2021 (Actual)
- Primary completion
- Feb 15, 2024 (Actual)
- Completion
- Dec 29, 2028 (Estimated)
- Last update posted
- Nov 6, 2025
2021 – 2028
United States locations
- U.S. sites
- 28
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Anthos Investigative Site | Huntsville | Alabama | 35801 | — |
| Anthos Investigative Site | Mobile | Alabama | 36608 | — |
| Anthos Investigative Site | Stamford | Connecticut | 06905 | — |
| Anthos Investigative Site | Clearwater | Florida | 33756 | — |
| Anthos Investigative Site | Daytona Beach | Florida | 32114-2321 | — |
| Anthos Investigative Site | Largo | Florida | 33777 | — |
| Anthos Investigative Site | Safety Harbor | Florida | 34695 | — |
| Anthos Investigative Site | Saint Augustine | Florida | 32086 | — |
| Anthos Investigative Site | Johns Creek | Georgia | 30024 | — |
| Anthos Investigative Site | Owensboro | Kentucky | 42303 | — |
| Anthos Investigative Site | Baltimore | Maryland | 21229-5222 | — |
| Anthos Investigative Site | Salisbury | Maryland | 21804 | — |
| Anthos Investigative Site | Framingham | Massachusetts | 01701 | — |
| Anthos Investigative Site | Haverhill | Massachusetts | 01830 | — |
| Anthos Investigative Site | Lansing | Michigan | 48912 | — |
| Anthos Investigative Site | Sewell | New Jersey | 08080 | — |
| Anthos Investigative Site | Poughkeepsie | New York | 12601 | — |
| Anthos Investigative Site | Southampton | New York | 11968 | — |
| Anthos Investigative Site | Lenoir | North Carolina | 28645 | — |
| Anthos Investigative Site | Fargo | North Dakota | 58104 | — |
| Anthos Investigative Site | Oklahoma City | Oklahoma | 73135 | — |
| Anthos Investigative Site | Camp Hill | Pennsylvania | 17011 | — |
| Anthos Investigative Site | Kingsport | Tennessee | 37660 | — |
| Anthos Investigative Site | Kingwood | Texas | 77339 | — |
| Anthos Investigative Site | Odessa | Texas | 79761-5133 | — |
| Anthos Investigative Site | Tomball | Texas | 77375 | — |
| Anthos Investigative Site | Falls Church | Virginia | 22042 | — |
| Anthos Investigative Site | Manassas | Virginia | 20109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04755283, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 6, 2025 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04755283 live on ClinicalTrials.gov.