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Terminated Phase 3 Interventional Results available

A Study of Prucalopride For Functional Constipation in Children and Teenagers

ClinicalTrials.gov ID: NCT04759833

Public ClinicalTrials.gov record NCT04759833. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 1:46 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3, Multicenter, Randomized Study With 2 Different Doses of Prucalopride Administered to Male and Female Pediatric Subjects Aged 6 Months to 17 Years With Functional Constipation, Consisting of a 12-week Double-blind, Placebo-controlled Part (Part A) to Evaluate Efficacy and Safety Followed by a 36-week Double-blind Extension Part (Part B) to Document Long-term Safety up to Week 48

Study identification

NCT ID
NCT04759833
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Takeda
Industry
Enrollment
175 participants

Conditions and interventions

Conditions

Interventions

  • Prucalopride Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
6 Months to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 12, 2021
Primary completion
Nov 12, 2023
Completion
Nov 12, 2023
Last update posted
Jun 5, 2024

2021 – 2023

United States locations

U.S. sites
41
U.S. states
19
U.S. cities
35
Facility City State ZIP Site status
Phoenix Children's Hospital Phoenix Arizona 85016
Novak Clinical Research Tucson Arizona 85741
Eclipse Clinical Research Tucson Arizona 85745
Advanced Research Center, Inc. Anaheim California 92805
Children's Hospital of Orange County Orange California 92868
University of California, Davis Department of Pediatrics Sacramento California 95817
University of California San Francisco California 94158
University of Colorado Denver Aurora Colorado 80045
Medstar Georgetown University Hospital Washington D.C. District of Columbia 20016
Direct Helpers Research Center Hialeah Florida 33012
Pediatric & Adult Research Center Kissimmee Florida 34741
Auzmer Research Lakeland Florida 33813
University of Miami - Miller School of Medicine Miami Florida 33136
Nicklaus Children's Hospital Miami Florida 33155
Florida Research Center, Inc. Miami Florida 33174
Orlando Health - APH Center for Digestive Health and Nutrition Orlando Florida 32806
The University of Chicago Medical Center Chicago Illinois 60637
GI Pediatric Subspecialty Clinic Peoria Illinois 61603
Methodist Medical Center of Illinois Peoria Illinois 61636
Riley Hospital for Children at Indiana University Health Indianapolis Indiana 46202
Willis-Knighton Center for Pediatric Gastroenterology & Advanced Endoscopy Shreveport Louisiana 71118
Massachusetts General Hospital Boston Massachusetts 02114
Boston Children's Hospital Boston Massachusetts 02115
Baystate Health Springfield Massachusetts 01199
Cardinal Glennon Children's Medical Center St Louis Missouri 63104
Jersey Shore University Medical Center Neptune City New Jersey 07753
CUMC Pediatrics-GI New York New York 10032
Cleveland Clinic Cleveland Ohio 44195
Cyn3rgy Research & Development Gresham Oregon 97030
Oregon Health & Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
GI For Kids Knoxville Tennessee 37922
Le Bonheur Children's Hospital Memphis Tennessee 38105
Tekton Research, Inc. Beaumont Texas 77706
Cedar Health Research Dallas Texas 75251
Allure Health LLC Friendswood Texas 77546
Texas Children's Hospital Houston Texas 77030
Pediatric Associates Houston Texas 77087
Pediatric Center Richmond Texas 77469
University of Utah Salt Lake City Utah 84108
Pediatric Specialist of Virginia Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04759833, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 5, 2024 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04759833 live on ClinicalTrials.gov.

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