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Completed Phase 3 Interventional

Open-label Trial in Parkinson's Disease (PD)

ClinicalTrials.gov ID: NCT04760769

Public ClinicalTrials.gov record NCT04760769. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

58-Week Open-label Trial of Tavapadon in Parkinson's Disease (TEMPO-4 Trial)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and efficacy of long-term administration of flexible doses of tavapadon in participants with Parkinson's Disease.

Study identification

NCT ID
NCT04760769
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
AbbVie
Industry
Enrollment
992 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 23, 2021
Primary completion
Nov 30, 2025
Completion
Nov 30, 2025
Last update posted
Dec 22, 2025

2021 – 2025

United States locations

U.S. sites
52
U.S. states
24
U.S. cities
51
Facility City State ZIP Site status
Birmingham, Alabama Birmingham Alabama 35233
Pheonix, Arizona Phoenix Arizona 85004
Little Rock, Arkansas Little Rock Arkansas 72205
Fountain Valley, California Fountain Valley California 92708
Fresno, California Fresno California 93710
Los Angeles, California Los Angeles California 90048
Pasadena, California Pasadena California 91105
Reseda, California Reseda California 91335
Englewood, Colorado Englewood Colorado 80113
Florida, United States Adventura Florida 33180
Boca Raton, Florida Boca Raton Florida 33486
Coral Springs, Florida Coral Springs Florida 33067
Maitland, Florida Maitland Florida 32751
Naples, Florida Naples Florida 34102
Ocala, Florida Ocala Florida 34470
Port Charlotte, Florida Port Charlotte Florida 33980
Port Orange, Florida Port Orange Florida 32127
Tampa, Florida Tampa Florida 33615
Winter Park, Florida Winter Park Florida 32792
Augusta, Georgia Augusta Georgia 30912
Chicago, Illinois Chicago Illinois 60612
Winfield, Illinois Winfield Illinois 60190
Kansas City Kansas City Kansas 66160
Lexington, Kentucky Lexington Kentucky 40536
Scarborough, Maine Scarborough Maine 04074
Boston, Massachusettes Boston Massachusetts 02215
Lawrence, Massachusetts Lawrence Massachusetts 01843
East Lansing, Michigan East Lansing Michigan 48824
West Bloomfield West Bloomfield Michigan 48322
Las Vegas, Nevada Las Vegas Nevada 89106
Camden, New Jersey Camden New Jersey 08103
Albany, New York Albany New York 12208
Syracuse, New York Syracuse New York 13210
Asheville, North Carolina Asheville North Carolina 28806
Durham, North Carolina Durham North Carolina 27705
Cincinnati, Ohio Cincinnati Ohio 45212
Cleveland, Ohio Cleveland Ohio 44195
Columbus, Ohio Columbus Ohio 43221
Dayton, Ohio Dayton Ohio 45459
Toledo, Ohio Toledo Ohio 43614
Philadelphia, Pennsylvania Philadelphia Pennsylvania 19107
Memphis, Tennessee Memphis Tennessee 38157
Georgetown, Texas Georgetown Texas 78628
Houston, Texas Houston Texas 77030
Lubbock, Texas Lubbock Texas 79410
Round Rock, Texas Round Rock Texas 78681
Burlington, Vermont Burlington Vermont 05401
Richmond, Virginia Richmond Virginia 23229
Richmond, Virginia Richmond Virginia 23233
Virginia Beach, Virginia Virginia Beach Virginia 23456
Kirkland, Washington Kirkland Washington 98034
Spokane, Washington Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 88 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04760769, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 22, 2025 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04760769 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →