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Terminated Phase 2 Interventional Results available

SYMPHONY-2, A Trial to Examine Combination of Tazemetostat With Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma

ClinicalTrials.gov ID: NCT04762160

Public ClinicalTrials.gov record NCT04762160. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 6:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

SYMPHONY-II: A Phase II Open-Label, Multicenter Trial of Oral Tazemetostat in Combination With Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study evaluates the safety and efficacy of combining the EZH2 inhibitor tazemetostat with rituximab in R/R FL subjects previously treated with at least 2 standard prior systemic treatment regimens where at least 1 anti-CD20-based regimen was used.

Study identification

NCT ID
NCT04762160
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Epizyme, Inc.
Industry
Enrollment
5 participants

Conditions and interventions

Interventions

Drug · Combination Product

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 15, 2020 (Actual)
Primary completion
Mar 22, 2022 (Actual)
Completion
Mar 22, 2022 (Actual)
Last update posted
Mar 25, 2024

2020 – 2022

United States locations

U.S. sites
20
U.S. states
12
U.S. cities
20
Facility City State ZIP Site status
Alabama Oncology Birmingham Alabama 35223 —
Compassionate Cancer Care Fountain Valley California 92708 —
USOR/Rocky Mountain Cancer Centers Boulder Colorado 80303 —
USOR/ Illinois Cancer Specialists Niles Illinois 60714 —
XCancer/ Northwest Oncology & Hematology Rolling Meadows Illinois 60008 —
Revive/Oakland Medical Group Farmington Hills Michigan 48336 —
Revive/Hematology Oncology Associates of Rockland Sterling Heights Michigan 48314 —
USOR/ NY Oncology Hematology Albany New York 12206 —
East Carolina University Greenville North Carolina 27858 —
USOR/ Oncology & Hematology Care Clinical Trials Cincinnati Ohio 45236 —
XCancer/Dayton Physicians Network Kettering Ohio 45409 —
XCancer/Tennessee Cancer Specialists Knoxville Tennessee 37909 —
USOR/ Texas Oncology Austin Texas 78705 —
USOR/Texas Oncology Dallas Texas 75230 —
USOR/ Texas Oncology San Antonio Texas 78240 —
USOR/ Texas Oncology Tyler Texas 75702 —
USOR/Texas Oncology Weslaco Texas 78596 —
USOR/Virginia Cancer Specialists Gainesville Virginia 20155 —
USOR/Oncology & Hematology Associates of Southwest Virginia Roanoke Virginia 24014 —
Swedish Cancer Institute Seattle Washington 98104 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04762160, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 25, 2024 · Synced Oct 27, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04762160 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →