Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)
Public ClinicalTrials.gov record NCT04768296. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Open-label, Single-arm Study of Berzosertib (M6620) in Combination With Topotecan in Participants With Relapsed Platinum-resistant Small-Cell Lung Cancer (DDRiver SCLC 250)
Study identification
- NCT ID
- NCT04768296
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- EMD Serono Research & Development Institute, Inc.
- Industry
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Interventions
- Berzosertib Drug
- Topotecan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2021
- Primary completion
- Jul 20, 2023
- Completion
- Jul 20, 2023
- Last update posted
- Sep 25, 2024
2021 – 2023
United States locations
- U.S. sites
- 12
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Medical Foundation | Santa Rosa | California | 95403 | — |
| St Joseph Heritage Healthcare | Santa Rosa | California | 95403 | — |
| Cotton-O'Neil Clinical Research Center, Hematology and Oncology | Topeka | Kansas | 66606 | — |
| National Cancer Institute | Bethesda | Maryland | 20892 | — |
| Cancer & Hematology Centers of Western Michigan | Grand Rapids | Michigan | 49546 | — |
| MidAmerica Cancer Care | Kansas City | Missouri | 64114 | — |
| NJ Center for Cancer Research | Brick | New Jersey | 08724 | — |
| Southeastern Medical Oncology Center | Goldsboro | North Carolina | 27534 | — |
| FirstHealth of the Carolinas, Inc. | Pinehurst | North Carolina | 28374 | — |
| Summa Health | Akron | Ohio | 44304 | — |
| Toledo Clinic | Toledo | Ohio | 43623 | — |
| Millennium Physicians Association, LLP | Houston | Texas | 77090 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04768296, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2024 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04768296 live on ClinicalTrials.gov.