Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma
Public ClinicalTrials.gov record NCT04768881. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Open-Label Multicenter Study to Evaluate the Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma
Study identification
- NCT ID
- NCT04768881
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Karyopharm Therapeutics Inc
- Industry
- Enrollment
- 15 participants
Conditions and interventions
Interventions
- Selinexor Drug
- Pembrolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2021
- Primary completion
- Sep 21, 2023
- Completion
- Sep 21, 2023
- Last update posted
- Aug 22, 2024
2021 – 2023
United States locations
- U.S. sites
- 13
- U.S. states
- 8
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA | Los Angeles | California | 90095 | — |
| TOI Clinical Research | Pasadena | California | 91105 | — |
| BRCR Global | Plantation | Florida | 33322 | — |
| Minnesota Oncology Hematology | Minneapolis | Minnesota | 55404 | — |
| Great Plains Health | North Platte | Nebraska | 69101 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | — |
| New York Oncology Hematology | Albany | New York | 12206 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| OH Care Clinical Trials | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44144 | — |
| Texas Oncology-Austin Central | Austin | Texas | 78731 | — |
| Texas Oncology - Baylor Sammons Center | Dallas | Texas | 75246 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04768881, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 22, 2024 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04768881 live on ClinicalTrials.gov.