An Efficacy and Safety Study of ALZ-801 in APOE4/4 Early AD Subjects
Public ClinicalTrials.gov record NCT04770220. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Efficacy, Safety and Biomarker Effects of ALZ-801 in Subjects With Early Alzheimer's Disease and APOE4/4 Genotype
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the APOE4/4 genotype. This is a double-blind, randomized trial with one dose of ALZ-801 compared to placebo.
Study identification
- NCT ID
- NCT04770220
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 325 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 19, 2021 (Actual)
- Primary completion
- May 29, 2024 (Actual)
- Completion
- Jul 29, 2024 (Actual)
- Last update posted
- Sep 29, 2026
2021 – 2024
United States locations
- U.S. sites
- 55
- U.S. states
- 21
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience | Phoenix | Arizona | 85004 | — |
| CCT Research | Scottsdale | Arizona | 85297 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| ATP Clinical Research | Costa Mesa | California | 92626 | — |
| Tilda Research | Irvine | California | 92780 | — |
| UCSD Shiley-Marcos Alzheimer's Disease Research Center | La Jolla | California | 92037 | — |
| Torrance Clinical Research Institute | Lomita | California | 90717 | — |
| Collaborative NeuroScience Network LLC | Long Beach | California | 90806 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| SC3 Research Group | Pasadena | California | 91105 | — |
| Sutter Health | Sacramento | California | 95816 | — |
| JEM Research Institute, Headlands Site | Atlantis | Florida | 33462 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| Galiz Research | Hialeah | Florida | 33016 | — |
| Alphab Global Research | Jupiter | Florida | 33458 | — |
| Charter Research | Lady Lake | Florida | 32159 | — |
| K2 Medical Research, LLC | Maitland | Florida | 32751 | — |
| Miami Jewish Health | Miami | Florida | 33137 | — |
| Y & L Advance Health Care, Inc /DBA Elite Clinical Research | Miami | Florida | 33144 | — |
| Mount Sinai Medical Center | Miami Beach | Florida | 33140 | — |
| Aqualane Clinical Research | Naples | Florida | 34105 | — |
| Charter Research | Orlando | Florida | 32803 | — |
| Headlands Research Orlando | Orlando | Florida | 32819 | — |
| Advanced Research Consultants | Palm Beach Gardens | Florida | 33410 | — |
| Quantum CNS Clinical Research | Pompano Beach | Florida | 33064 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| ALZ Research and Treatment Center (A.R.T.C.) | Stuart | Florida | 34997 | — |
| ALZ Research and Treatment Center (A.R.T.C.) | Wellington | Florida | 33414 | — |
| Premiere Research Institute | West Palm Beach | Florida | 33407 | — |
| Columbus Memory Center | Columbus | Georgia | 31909 | — |
| Sandhill Research, LLC | Decatur | Georgia | 30030 | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | 46804 | — |
| Louisiana State University Health Sciences Center (LSUHSC) | Shreveport | Louisiana | 71103 | — |
| Headlands Research Eastern MA | Plymouth | Massachusetts | 02360 | — |
| WR-CRCN | Las Vegas | Nevada | 89106 | — |
| Advanced Memory Research Center | Toms River | New Jersey | 08755 | — |
| Neurological Associates of Albany | Albany | New York | 12208 | — |
| NYU Alzheimer's Disease Research Center | New York | New York | 10016 | — |
| Kline Institute for Psychiatric Research | Orangeburg | New York | 10962 | — |
| University of Rochester Medical Center | Rochester | New York | 14620 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10312 | — |
| Triad Clinical Trials | Greensboro | North Carolina | 27410 | — |
| AMC Research | Matthews | North Carolina | 28105 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| Neurology Diagnostics, Inc. | Dayton | Ohio | 45459 | — |
| IPS Research | Oklahoma City | Oklahoma | 73106 | — |
| Center for Cognitive Health | Portland | Oregon | 97225 | — |
| Abington Neurological Associates | Abington | Pennsylvania | 19001 | — |
| Lehigh Center for Clinical Research | Allentown | Pennsylvania | 18104 | — |
| Rhode Island Mood & Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Vanderbilt Center for Cognitive Medicine | Nashville | Tennessee | 37212 | — |
| UT Health Science Center at Houston | Houston | Texas | 77054 | — |
| Re:Cognition Health | Fairfax | Virginia | 22031 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04770220, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04770220 live on ClinicalTrials.gov.