A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin
Public ClinicalTrials.gov record NCT04770532. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 26-week Trial Comparing the Effect and Safety of Once Weekly Insulin Icodec and Once Daily Insulin Degludec, Both With or Without Non-insulin Anti-diabetic Drugs, in Subjects With Type 2 Diabetes Treated With Basal Insulin
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin degludec taken daily. Participants will either get insulin icodec that participants will have to inject once a week on the same day of the week or insulin degludec that participants will have to inject once a day at the same time every day. Which treatment participants get is decided by chance. The insulin is injected with a needle in a skin fold in the thigh, upper arm or stomach. The study will last for about 8 months. Participants will have 17 clinic visits and 13 phone calls with the study doctor. At 8 clinic visits participants will have blood samples taken. At 4 clinic visits participants cannot eat or drink (except for water) for 8 hours before the visit. Participants will be asked to wear a sensor that measures their blood sugar all the time in 3 periods for a total of 13 weeks (about 3 months) during the study. Women cannot take part if pregnant, breast-feeding or plan to become pregnant during the study period.
Study identification
- NCT ID
- NCT04770532
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 526 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 4, 2021
- Primary completion
- Jan 26, 2022
- Completion
- Feb 28, 2022
- Last update posted
- Dec 14, 2025
2021 – 2022
United States locations
- U.S. sites
- 38
- U.S. states
- 13
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| American Clinical Trials | Buena Park | California | 90620 | — |
| Cedars-Sinai Medical Group | Encino | California | 91436 | — |
| Valley Research | Fresno | California | 93720 | — |
| Diabetes/Lipid Mgmt & Res Ctr | Huntington Beach | California | 92648 | — |
| Scripps Whittier Diabetes Inst | La Jolla | California | 92037 | — |
| Clinical Trials Research_Sacramento | Lincoln | California | 95648 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Desert Oasis Hlthcr Med Group | Palm Springs | California | 92262 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Atlanta Diabetes Associates | Atlanta | Georgia | 30318 | — |
| Endo Res Solutions Inc | Roswell | Georgia | 30076 | — |
| Velocity Clin. Res Valparaiso | Valparaiso | Indiana | 46383 | — |
| Four Rivers Clinical Research Inc | Paducah | Kentucky | 42001 | — |
| New Orleans Center for Clinical Research | New Orleans | Louisiana | 70119 | — |
| Ileana J Tandron APMC | Slidell | Louisiana | 70461-4231 | — |
| Endo And Metab Cons | Rockville | Maryland | 20852 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115-5804 | — |
| MassResearch, LLC | Waltham | Massachusetts | 02453 | — |
| Palm Research Center Inc. | Las Vegas | Nevada | 89148 | — |
| AMC Community Endocrinology | Albany | New York | 12203 | — |
| Northport VA Med Ctr Northport | Northport | New York | 11768 | — |
| Mountain Diabetes & Endocrine Center | Asheville | North Carolina | 28803 | — |
| PharmQuest Life Sciences LLC | Greensboro | North Carolina | 27408 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| Amarillo Med Spec LLP | Amarillo | Texas | 79106 | — |
| Osvaldo A. Brusco MD PA | Corpus Christi | Texas | 78414 | — |
| Thyroid, Endocrinology, and Diabetes, PA | Dallas | Texas | 75208 | — |
| Baylr Sctt White Rs Inst, Endo | Dallas | Texas | 75226 | — |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| Diabetes and Thyroid Ctr of FW | Fort Worth | Texas | 76132 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Simcare Medical Research, LLC | Sugar Land | Texas | 77478 | — |
| Hillcrest Family Health Center | Waco | Texas | 76708 | — |
| Capital Clin Res Ctr,LLC | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04770532, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced Sep 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04770532 live on ClinicalTrials.gov.