A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)
Public ClinicalTrials.gov record NCT04772885. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Randomized, Placebo-controlled, Single and Multiple Ascending Dose Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)
Study identification
- NCT ID
- NCT04772885
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Kymera Therapeutics, Inc.
- Industry
- Enrollment
- 154 participants
Conditions and interventions
Interventions
- KT-474/Placebo Drug
- KT-474 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 22, 2021
- Primary completion
- Oct 19, 2022
- Completion
- Oct 19, 2022
- Last update posted
- Oct 23, 2022
2021 – 2022
United States locations
- U.S. sites
- 14
- U.S. states
- 6
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Dermatology Specialists | Phoenix | Arizona | 85006 | — |
| Southwest Skin Specialists 32nd St | Phoenix | Arizona | 85018 | — |
| Southwest Skin Specialists Tatum | Phoenix | Arizona | 85028 | — |
| Beatrice Keller Clinic | Sun City West | Arizona | 85375 | — |
| Encore Medical Research, LLC. - Boynton Beach | Boynton Beach | Florida | 33436 | — |
| Research Centers of America | Hollywood | Florida | 22024 | — |
| Encore Medical Research, LLC. - Hollywood | Hollywood | Florida | 33021 | — |
| Encore Medical Research, LLC. - Weston | Weston | Florida | 33331 | — |
| Dermatology and Skin Cancer Center of Leawood | Leawood | Kansas | 66211 | — |
| Dermatology and Skin Cancer Center of Overland Park | Overland Park | Kansas | 66223 | — |
| Dermatology and Skin Cancer Center of Lee's Summit | Lee's Summit | Missouri | 64064 | — |
| TKL Research | Fair Lawn | New Jersey | 07410 | — |
| U.S. Dermatology Partners Jollyville | Austin | Texas | 78759 | — |
| U.S. Dermatology Partners Cedar Park | Cedar Park | Texas | 78613 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04772885, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 23, 2022 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04772885 live on ClinicalTrials.gov.