Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
Public ClinicalTrials.gov record NCT04788511. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effect of Semaglutide 2.4 mg Once Weekly on Function and Symptoms in Subjects With Obesity-related Heart Failure With Preserved Ejection Fraction
Study identification
- NCT ID
- NCT04788511
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 529 participants
Conditions and interventions
Conditions
Interventions
- Placebo (semaglutide) Drug
- Semaglutide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 15, 2021
- Primary completion
- Apr 17, 2023
- Completion
- Apr 17, 2023
- Last update posted
- Dec 4, 2025
2021 – 2023
United States locations
- U.S. sites
- 50
- U.S. states
- 24
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Eastern Shore Rsrch Inst, LLC | Fairhope | Alabama | 36532 | — |
| National Heart Institute Cal | Beverly Hills | California | 90211 | — |
| Keck Medical Center of USC - Outpatient Clinic | Los Angeles | California | 90033 | — |
| Lundquist Inst-Biomed Innovtn | Torrance | California | 90502 | — |
| Jacksonville Ctr For Clin Res | Jacksonville | Florida | 32216 | — |
| First Coast Cardiovascular Institute | Jacksonville | Florida | 32257 | — |
| Baptist Heart Specialists_Jacksonville | Jacksonville | Florida | 32258 | — |
| CV Res Ctr of S Florida | Miami | Florida | 33173 | — |
| Endeavor Health Clinical Operations-NCH | Arlington Heights | Illinois | 60005 | — |
| University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Endeavor Health Glenbook Hosp | Evanston | Illinois | 60201 | — |
| Northwestern University_Chicago_0 | Evanston | Illinois | 60208 | — |
| Chicago Medical Research LLC | Hazel Crest | Illinois | 60429 | — |
| Ascension St. Vincent Medical Group | Indianapolis | Indiana | 46260 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center_Kansas City | Kansas City | Kansas | 66160 | — |
| Cotton-O'Neil Heart Center | Topeka | Kansas | 66606 | — |
| The Research Group of Lexington LLC | Lexington | Kentucky | 40503 | — |
| Baptist Health Louisville | Louisville | Kentucky | 40207 | — |
| Baptist Health Madisonville, Inc | Madisonville | Kentucky | 42431 | — |
| Grace Research, LLC | Bossier City | Louisiana | 71111 | — |
| Heart Clinic of Hammond | Hammond | Louisiana | 70403 | — |
| Grace Research, LLC_Shreveport | Shreveport | Louisiana | 71105 | — |
| Louisiana Heart Center_Slidell | Slidell | Louisiana | 70458 | — |
| Louisiana Heart Center | Slidell | Louisiana | 70458 | — |
| Ascension Saint Agnes Heart Ca | Baltimore | Maryland | 21229 | — |
| John Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202-2689 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55902 | — |
| Univ of Mississippi Med Ctr | Jackson | Mississippi | 39216 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| St Louis Heart & Vascular, P.C. | St Louis | Missouri | 63136 | — |
| Bryan Heart | Lincoln | Nebraska | 68506 | — |
| CHI Health Clinic Cardiology (CUMC - Bergan Mercy) | Omaha | Nebraska | 68124 | — |
| St Francis Hospital Lindner Research Center | Greenvale | New York | 11548 | — |
| NY Presbyt Hosp-W Cornell Med | New York | New York | 10021 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Wake Forest School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Lindner Center,Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Hospital of University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Medical Univ of South Carolina_Charleston_0 | Charleston | South Carolina | 29425 | — |
| Sanford Health_Sioux Falls | Sioux Falls | South Dakota | 57117 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84132 | — |
| Cardiology Consultants of Danville Inc. | Danville | Virginia | 24541 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Sentara Health Research Center | Norfolk | Virginia | 23507 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298-5058 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04788511, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 4, 2025 · Synced Apr 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04788511 live on ClinicalTrials.gov.