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Completed Phase 3 Interventional Results available

A Research Study to Compare Two Types of Insulin, a New Insulin, Insulin Icodec and an Available Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)

ClinicalTrials.gov ID: NCT04795531

Public ClinicalTrials.gov record NCT04795531. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 9:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 26-week Double Blinded, Multiregional, Trial Comparing the Effect and Safety of Once Weekly Insulin Icodec and Once Daily Insulin Degludec 100 Units/mL, Both in Combination With Non-insulin Anti-diabetic Drugs, in Insulin naïve Subjects With Type 2 Diabetes.

Study identification

NCT ID
NCT04795531
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
588 participants

Conditions and interventions

Interventions

  • Insulin degludec Drug
  • Insulin icodec Drug
  • Placebo insulin degludec Drug
  • Placebo insulin icodec Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 23, 2021
Primary completion
Jun 22, 2022
Completion
Jun 22, 2022
Last update posted
Dec 3, 2024

2021 – 2022

United States locations

U.S. sites
26
U.S. states
14
U.S. cities
25
Facility City State ZIP Site status
Lakeview Clinical Research, LLC Guntersville Alabama 35976
American Clinical Trials Buena Park California 90620
Headlands Research California, LLC Escondido California 92025
Valley Research Fresno California 93720
First Valley Medical Group Lancaster California 93534
Est Cst Inst for Rsrch,Jksnvil Jacksonville Florida 32216
Palm Harbor Medical Associates Palm Harbor Florida 34684-3609
Metabolic Research Institute Inc West Palm Beach Florida 33401
Cedar-Crosse Research Center Chicago Illinois 60607
Cotton-Oneill Diabetes and End Topeka Kansas 66606-2806
Arcturus Healthcare, PLC Troy Michigan 48098
Southgate Medical Group, LLP West Seneca New York 14224
Physician's East Endocrinology Greenville North Carolina 27834
Accellacare Wilmington North Carolina 28401
Diab & Endo Assoc of Stark Co Canton Ohio 44718
Providence Health Partners Ctr Dayton Ohio 45439
Prestige Clinical Research Franklin Ohio 45005
Intend Research Norman Oklahoma 73069
Hillcrest Clinical Research Simpsonville South Carolina 29681-1538
Velocity Clinical Res-Dallas Dallas Texas 75230
UT Southwestern Med Cntr Dallas Texas 75390-9302
PrimeCare Medical Group Houston Texas 77024
Texas Diab & Endo, P.A. Round Rock Texas 78681
Clinical Trials of Texas, LLC San Antonio Texas 78229
Chrysalis Clinical Research St. George Utah 84790
Rainier Clin Res Ctr Inc Renton Washington 98057

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04795531, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 3, 2024 · Synced May 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04795531 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →