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Terminated Phase 1 Interventional

Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 is Administered in Combination With IV Modified FOLFIRINOX (mFFX) With or Without IV Budigalimab Compared to mFFX in Adult Participants With Untreated Pancreatic Cancer Metastasis

ClinicalTrials.gov ID: NCT04807972

Public ClinicalTrials.gov record NCT04807972. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 6:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2, Randomized, Controlled, Open-Label Study Evaluating the Safety and Efficacy of ABBV-927 Administered in Combination With Modified FOLFIRINOX (mFFX) With or Without Budigalimab Compared to mFFX in Subjects With Untreated Metastatic Pancreatic Adenocarcinoma

Study identification

NCT ID
NCT04807972
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
AbbVie
Industry
Enrollment
40 participants

Conditions and interventions

Interventions

  • ABBV-927 Drug
  • Budiglimab Drug
  • modified FOLFIRINOX Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 27, 2021
Primary completion
Mar 24, 2024
Completion
Mar 24, 2024
Last update posted
Jan 6, 2025

2021 – 2024

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
UCHSC Anschultz Cancer Pavilion /ID# 227841 Aurora Colorado 80045-2517
Johns Hopkins Hospital /ID# 226713 Baltimore Maryland 21287
Univ Hosp Cleveland /ID# 226807 Cleveland Ohio 44106
Cleveland Clinic Main Campus /ID# 231135 Cleveland Ohio 44195
Penn State Hershey Medical Ctr /ID# 229837 Hershey Pennsylvania 17033-2360

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04807972, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 6, 2025 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04807972 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →