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Terminated Phase 1 Interventional

Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

ClinicalTrials.gov ID: NCT04810611

Public ClinicalTrials.gov record NCT04810611. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 7:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib, Multicenter, Open-label Platform Study of Select Drug Combinations in Adult Patients With Lower Risk (Very Low, Low, or Intermediate Risk) Myelodysplastic Syndrome

Study identification

NCT ID
NCT04810611
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Novartis Pharmaceuticals
Industry
Enrollment
33 participants

Conditions and interventions

Interventions

  • MBG453 Drug
  • NIS793 Drug
  • canakinumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 17, 2021
Primary completion
Apr 18, 2024
Completion
Apr 18, 2024
Last update posted
Oct 9, 2025

2021 – 2024

United States locations

U.S. sites
5
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
City Of Hope National Med Center Oncology Duarte California 91010
H Lee Moffitt Cancer Center and Research Institute Tampa Florida 33612
Massachusetts General Hospital . Boston Massachusetts 02114
The Ohio State University Wexner Medical Center . Columbus Ohio 43210
MD Anderson Cancer Center/University of Texas MD Anderson Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04810611, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 9, 2025 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04810611 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →