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Completed Phase 1Phase 2 Interventional

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

ClinicalTrials.gov ID: NCT04815720

Public ClinicalTrials.gov record NCT04815720. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 6:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2 Study of the Combination of Pepinemab and Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Study identification

NCT ID
NCT04815720
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Vaccinex Inc.
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

  • pepinemab + pembrolizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 100 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 8, 2021
Primary completion
Jul 23, 2024
Completion
Jul 23, 2024
Last update posted
Jan 7, 2025

2021 – 2024

United States locations

U.S. sites
15
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Highlands Oncology Group, PA - North Hills Springdale Arkansas 72762
California Cancer Associates for Research and Excellence (CCARE)-Fresno Fresno California 93720
UCSF Medical Center at Mission Bay San Francisco California 94158
Yale Cancer Center New Haven Connecticut 06510
AdventHealth Celebration Celebration Florida 34747
AdventHealth Orlando Orlando Florida 32803
Emory Saint Joseph's Hospital Atlanta Georgia 30308
American Oncology Partners of Maryland, PA Bethesda Maryland 20817
Siteman Cancer Center - Washington University Medical Campus St Louis Missouri 63110
Northwell Health - Centers for Advanced Medicine Lake Success New York 11042
University of Rochester Rochester New York 14642
Messino Cancer Centers Asheville North Carolina 28806
Gabrail Cancer Research Center Canton Ohio 44718
Allegheny General Hospital Pittsburgh Pennsylvania 15212
Virginia Cancer Specialists - Fairfax Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04815720, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 7, 2025 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04815720 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →