Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy
Public ClinicalTrials.gov record NCT04816916. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of AXA1665 in Subjects With Liver Cirrhosis and Prior Overt Hepatic Encephalopathy (EMMPOWER)
Study identification
- NCT ID
- NCT04816916
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Axcella Health, Inc
- Industry
- Enrollment
- 12 participants
Conditions and interventions
Conditions
Interventions
- AXA1665 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 28, 2021
- Primary completion
- Jun 29, 2022
- Completion
- Jun 29, 2022
- Last update posted
- Jul 26, 2022
2021 – 2022
United States locations
- U.S. sites
- 21
- U.S. states
- 11
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, San Francisco (UCSF) | San Francisco | California | 94143 | — |
| OMEGA Research Consultants | DeBary | Florida | 32713 | — |
| UF Hepatology Research at CTRB | Gainesville | Florida | 32610 | — |
| Homestead Associates in Research | Miami | Florida | 33032 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| New York University (NYU) School of Medicine | New York | New York | 10016 | — |
| Weill Medical College of Cornell University | New York | New York | 10021 | — |
| Cumberland Research Associates | Fayetteville | North Carolina | 28304 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina (MUSC) | Charleston | South Carolina | 29425 | — |
| Optimed Research | Edinburg | Texas | 78359 | — |
| Baylor Scott & White Research Institute | Fort Worth | Texas | 75246 | — |
| Advanced Liver Therapies at St. Luke's Episcopal Hospital | Houston | Texas | 77030 | — |
| Pinnacle Clinical Research | San Antonio | Texas | 78229 | — |
| University of Virginia School of Medicine | Charlottesville | Virginia | 22903 | — |
| Bon Secours Liver Institute | Newport News | Virginia | 23602 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23114 | — |
| McGuire Research Institute, Inc., McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04816916, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 26, 2022 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04816916 live on ClinicalTrials.gov.