A Study of TAK-994 in Adults With Narcolepsy
Public ClinicalTrials.gov record NCT04820842. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Dose-Blind Extension Study With Double-blind, Placebo-Controlled, Randomized Withdrawal Period to Evaluate the Safety and Explore the Pharmacokinetics and Pharmacodynamics of TAK-994 in Adults With Narcolepsy With Cataplexy (Narcolepsy Type 1)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Adults with narcolepsy who have completed the TAK-994-1501 study will be able to take part in this study. The main aim of this study is to check if participants have side effects from TAK-994. Participants will take one of 3 different TAK-994 dose for 8 weeks. Then, half the participants will continue with their dose of TAK-994 and half will take a placebo. In this study, a placebo will look like a TAK-994 tablet but will not have any medicine in it. Participants will take TAK-994 or placebo for 4 weeks. Participants will visit the clinic for a final check-up 2 weeks after their last dose of TAK-994 or placebo. The study doctors will check for side effects from TAK-994 and placebo throughout the study. Participants will continue to record any narcolepsy symptoms as they did in Part B of the TAK 994-1501 study.
Study identification
- NCT ID
- NCT04820842
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 26 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2021 (Actual)
- Primary completion
- Nov 3, 2021 (Actual)
- Completion
- Nov 3, 2021 (Actual)
- Last update posted
- Dec 26, 2023
2021
United States locations
- U.S. sites
- 35
- U.S. states
- 16
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Wright Clinical Research | Alabaster | Alabama | 35007 | — |
| Mayo Clinic Arizona 300151190 | Phoenix | Arizona | 85054 | — |
| CITrials - Bellflower | Bellflower | California | 90706 | — |
| Santa Monica Clinical Trials | Los Angeles | California | 90025 | — |
| Stanford School of Medicine | Redwood City | California | 94063 | — |
| Pacific Research Network, Inc 150118105 | San Diego | California | 92103 | — |
| SDS Clinical Trials, Inc. | Santa Ana | California | 92705 | — |
| Alpine Clinical Research Center 1024762 | Boulder | Colorado | 80301 | — |
| Delta Waves Sleep Disorders and Research Center 300148510 | Colorado Springs | Colorado | 80918 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765 | — |
| Sleep Medicine Specialists of South Florida | Miami | Florida | 33176 | — |
| Clinical Site Partners, LLC | Miami | Florida | 33186 | — |
| JSV Clinical Research Study, Inc | Tampa | Florida | 33624 | — |
| Florida Pulmonary Research Institute, LLC 300127039 | Winter Park | Florida | 32789 | — |
| NeuroTrials Research, Inc. 300116336 | Atlanta | Georgia | 30342 | — |
| Sleep Practitioners, LLC Macon | Macon | Georgia | 31210 | — |
| Clinical Research Institute 300169881 | Stockbridge | Georgia | 30281 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Fort Wayne Neurological Center 150711262 | Fort Wayne | Indiana | 46804 | — |
| University of Kansas Medical Center Research Institute, Inc. University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Helene A. Emsellem, MD PC trading as "The Center for Sleep & Wake Disorders" 150119420 | Chevy Chase | Maryland | 20815 | — |
| Beth Israel Deaconess Medical Center CardioVascular Institute | Boston | Massachusetts | 02215 | — |
| Research Carolina Elite | Denver | North Carolina | 28037 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| Raleigh Neurology Associates 300209729 | Raleigh | North Carolina | 27607 | — |
| Raleigh Neurology Associates,300209729 | Raleigh | North Carolina | 27607 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45245 | — |
| Intrepid Research | Cincinnati | Ohio | 45245 | — |
| The Cleveland Clinic Foundation 100428 | Cleveland | Ohio | 44195 | — |
| Ohio Sleep Medicine and Neuroscience Institute 186 | Dublin | Ohio | 43017 | — |
| Respiratory Specialists Berks Schuylkill Respiratory Specialists Ltd | Wyomissing | Pennsylvania | 19610 | — |
| Medical University of South Carolina (MUSC) PARENT | Charleston | South Carolina | 29425 | — |
| Bogan Sleep Consultants, LLC 150711087 | Columbia | South Carolina | 29201 | — |
| Sleep Therapy & Research Center 300151246 | San Antonio | Texas | 78229 | — |
| Comprehensive Sleep Medicine Associates | Sugar Land | Texas | 77478 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04820842, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 26, 2023 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04820842 live on ClinicalTrials.gov.