ClinicalTrials.gov record
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
ClinicalTrials.gov ID: NCT04822181
Public ClinicalTrials.gov record NCT04822181. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The Effect of Semaglutide in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will either get semaglutide or a dummy medicine - which treatment participants get is decided by chance. Participants will need to inject themselves with medicine under the skin. Participants will need to do this once a week. The study will last for about 5 years. Participants will have up to 21 clinic visits and 9 phone calls with the clinical staff during the study. Some of the clinic visits may be spread over more than one day. Participants with other chronic liver diseases cannot take part in this study. Women cannot take part in the study if they are pregnant, breast-feeding or plan to become pregnant during the study period.
Study identification
- NCT ID
- NCT04822181
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,205 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 1, 2021 (Actual)
- Primary completion
- Apr 25, 2029 (Estimated)
- Completion
- Apr 25, 2029 (Estimated)
- Last update posted
- Oct 13, 2026
2021 – 2029
United States locations
- U.S. sites
- 130
- U.S. states
- 33
- U.S. cities
- 103
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North AL Health Res, LLC | Huntsville | Alabama | 35801 | — |
| The Institute for Liver Health | Chandler | Arizona | 85224 | — |
| Inst-Liver Hlth dba AZ Liver H | Peoria | Arizona | 85381 | — |
| Inst. Liver H II dba AZ Liver H | Tucson | Arizona | 85712 | — |
| Del Sol Research Management, LLC | Tucson | Arizona | 85715 | — |
| ARcare Center for Clinical Research | Jonesboro | Arkansas | 72401 | — |
| ARcare Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| Arkansas Diagnostic Center, PA | Little Rock | Arkansas | 72205 | — |
| Gastroenterology & Liver Institute | Escondido | California | 92025 | — |
| Shang Wu M.D. Inc. | Hacienda Heights | California | 91745 | — |
| Scripps Whittier Diabetes Inst | La Jolla | California | 92037 | — |
| UCSD NAFLD Research Center | La Jolla | California | 92037 | — |
| OM Research LLC | Lancaster | California | 93534 | — |
| Digestive Hlth Res of SoCa | Long Beach | California | 90808 | — |
| OM Research LLC | Oxnard | California | 93030 | — |
| Cedars-Sinai Medical Center | Pasadena | California | 90048 | — |
| Pasedena Liver Center | Pasadena | California | 91105 | — |
| Inland Empire Clin Trials LLC | Rialto | California | 92377 | — |
| UC Davis Hlth -Midtwn Ambu Cen | Sacramento | California | 95817 | — |
| University of California, San Francisco | San Francisco | California | 94143 | — |
| San Jose Gastroenterology | San Jose | California | 95116 | — |
| Peak Gastro Assoc-Col Springs | Colorado Springs | Colorado | 80907 | — |
| Yale Ctr for Clin Invest | New Haven | Connecticut | 06519 | — |
| Encore Medical Research of Boynton Beach LLC | Boynton Beach | Florida | 33436 | — |
| Integrity Clinical Research, LLC | Doral | Florida | 33122 | — |
| Covenant Metabolic Specialists, Ft. Myers | Fort Myers | Florida | 33912 | — |
| University of Florida-CTRB | Gainesville | Florida | 32610 | — |
| Miguel Rebollar PA | Hialeah | Florida | 33012 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33016 | — |
| Florida Research Institute, LLC | Lakewood Rch | Florida | 34211-4930 | — |
| Sandhill Research, LLC | Maitland | Florida | 32751 | — |
| Tandem Clinical Research - Maitland | Maitland | Florida | 32751 | — |
| Optimus U, Corp | Miami | Florida | 33135 | — |
| Univ of Miami/Schiff Ctr | Miami | Florida | 33136 | — |
| Genoma Research Group, Inc | Miami | Florida | 33173 | — |
| IMIC Inc | Miami | Florida | 33176 | — |
| San Marcus Res Clin Miami Lakes | Miami Lakes | Florida | 33014 | — |
| Ocala GI Research | Ocala | Florida | 34471 | — |
| Sensible Healthcare LLC | Ocoee | Florida | 34761 | — |
| Covenant Metabolic Specialists LLC | Sarasota | Florida | 34240 | — |
| Headlands Research - Sarasota | Sarasota | Florida | 34243 | — |
| Theia Clinical Research Centers LLC | St. Petersburg | Florida | 33710 | — |
| ClinCloud, LLC | Viera E. | Florida | 32940 | — |
| Florida Medical Clinic Orlando Health | Zephyrhills | Florida | 33542 | — |
| Emory University Hospital | Atlanta | Georgia | 30322-1059 | — |
| Columbus Regional Research Institute | Columbus | Georgia | 31904 | — |
| Gastroenterology Assoc_ CGA | Macon | Georgia | 31201 | — |
| Gastroint Spec of Georgia | Marietta | Georgia | 30060 | — |
| Rush University Med. Cntr | Chicago | Illinois | 60612 | — |
| University Of Chicago | Chicago | Illinois | 60637 | — |
| Endeavor Health | Skokie | Illinois | 60077 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202 | — |
| Digestive Research Alliance of Michiana | South Bend | Indiana | 46635 | — |
| Iowa Digestive Disease Center | Clive | Iowa | 50325 | — |
| University Of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Kansas Medical Clinic, PA | Topeka | Kansas | 66606 | — |
| Tandem Clinical Research - Houma | Houma | Louisiana | 70363 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Tandem Clinical Research - Metairie | Metairie | Louisiana | 70006 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center, GI Research | Baltimore | Maryland | 21202 | — |
| Walter Reed Nat Mil Md Ctr | Bethesda | Maryland | 20889 | — |
| Woodholme Gastroenterology Associates | Glen Burnie | Maryland | 21061 | — |
| Boston Medical Center_Cary | Boston | Massachusetts | 02118 | — |
| University of Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905-0001 | — |
| Southern Therapy and Advanced Research LLC | Jackson | Mississippi | 39216 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Univ of Nebraska Medical CTR | Omaha | Nebraska | 68198-3020 | — |
| Jubilee Clinical Research, Inc. | Las Vegas | Nevada | 89106 | — |
| Sierra Clinical Research-Las Vegas | Las Vegas | Nevada | 89106 | — |
| AIG Digestive Disease Research | Florham Park | New Jersey | 07932 | — |
| Premier Health Research, LLC | Sparta | New Jersey | 07871 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| Weill Cornell Med Coll-NYPH | New York | New York | 10021 | — |
| Icahn Sch of Med-Mt Sinai Hosp | New York | New York | 10029 | — |
| AtriumHealth Liver Care, Pineville | Charlotte | North Carolina | 28210 | — |
| Northeast GI Research Division | Concord | North Carolina | 28027 | — |
| Duke Univ. Med CNTR_Durham_2 | Durham | North Carolina | 27710 | — |
| Ohio State Univ Wexner Med Ctr | Columbus | Ohio | 43210 | — |
| Objective GI | Springboro | Ohio | 45066 | — |
| CRIOH | Westlake | Ohio | 44145 | — |
| Options Health Research, LLC | Tulsa | Oklahoma | 74104 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822 | — |
| Pennsylvania State University | Hershey | Pennsylvania | 17033 | — |
| Univ of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107-5244 | — |
| UPMC Center for Liver Diseases | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC_Center for Liver Care | Pittsburgh | Pennsylvania | 15213 | — |
| Care Access Research, Pottsville | Pottsville | Pennsylvania | 17901 | — |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | — |
| Ocean St Clin Res Partnrs, LLC | Lincoln | Rhode Island | 02865 | — |
| Medical University Of South Carolina | Charleston | South Carolina | 29425 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37421 | — |
| Digestive Health Res-TSMC | Hermitage | Tennessee | 37076 | — |
| East Tennessee Research Institute | Johnson City | Tennessee | 37604 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| Amarillo Center for Clinical Research, Ltd. | Amarillo | Texas | 79106 | — |
| Texas Clin Res Inst, LLC | Arlington | Texas | 76012 | — |
| Liver Ins@ Mthdist DTX Med Cen | Dallas | Texas | 75203 | — |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| South Texas Research Institute | Edinburg | Texas | 78539 | — |
| Brooke Army Medical Ctr. | Fort Sam Houston | Texas | 78234 | — |
| GI Alliance Research | Fort Worth | Texas | 76104 | — |
| Bylr Coll Md-Ben Taub Gen Hos | Houston | Texas | 77030-1608 | — |
| Baylor College Of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Bipharma Informatic Inc. | Houston | Texas | 77043 | — |
| Houston Research Institute | Houston | Texas | 77079 | — |
| Biopharma Informatic | Houston | Texas | 77084 | — |
| Amir Ali Hassan, MD, PA | Houston | Texas | 77089 | — |
| Centex Studies - McAllen | McAllen | Texas | 78504 | — |
| LinQ Research, LLC | Pearland | Texas | 77584 | — |
| Amer. Rrsch Corp-TX Liver Inst | San Antonio | Texas | 78215 | — |
| Clinical Trials of Texas, LLC | San Antonio | Texas | 78229 | — |
| Mt Olympus Medical Research, LLC | Sugar Land | Texas | 77479 | — |
| Digestive Hlth Res of N Texas | Wichita Falls | Texas | 76301 | — |
| South Ogden Family Medicine/ CCT Research | Ogden | Utah | 84405 | — |
| Velocity Clinical Research, Riverton | Riverton | Utah | 84065 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| University Of Virginia Hospital | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| Bon Secours Richmond Community Hospital LLC | Richmond | Virginia | 23226 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| VCU Health System | Richmond | Virginia | 23298 | — |
| Gastroent Consult of SW VA | Roanoke | Virginia | 24014 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 428 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04822181, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04822181 live on ClinicalTrials.gov.