A Dose Finding, Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19
Public ClinicalTrials.gov record NCT04828161. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Multicenter Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19 - The "EMPATHY" Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to establish the antiviral efficacy of ensovibep against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, identify the optimal dose, and demonstrate its clinical value for treating COVID-19 in adult ambulatory patients.
Study identification
- NCT ID
- NCT04828161
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 407 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 10, 2021 (Actual)
- Primary completion
- Nov 18, 2021 (Actual)
- Completion
- Jan 27, 2022 (Actual)
- Last update posted
- Jan 27, 2026
2021 – 2022
United States locations
- U.S. sites
- 27
- U.S. states
- 11
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Jasper Summit Research, LLC | Jasper | Alabama | 35501 | — |
| Benchmark Southern California | Colton | California | 92324 | — |
| Ascada Research | Fullerton | California | 92835 | — |
| Pacific Neuropsychiatric Specialists | Mission Viejo | California | 92691 | — |
| Providence Family Medical Center | Redondo Beach | California | 90277 | — |
| Future Innovative Treatments | Colorado Springs | Colorado | 80907 | — |
| Boward Infectious Disease and Primary Care | Margate | Florida | 33063 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| Life Spring Research Foundation | Miami | Florida | 33155 | — |
| Bio-Medical Research, LLC | Miami | Florida | 33184 | — |
| Panax Clinical Research, LLC | Miami Lakes | Florida | 33014 | — |
| AdventHealth Tampa | Tampa | Florida | 33613 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Gwinnett Research Institute | Buford | Georgia | 30519 | — |
| IACT Health | Columbus | Georgia | 31904 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Centennial Medical Group - Research Department | Elkridge | Maryland | 21075 | — |
| Jefferson City Medical Group | Jefferson City | Missouri | 65109 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Wilmington Health | Wilmington | North Carolina | 28412 | — |
| VitaLink Research | Greenville | South Carolina | 29615 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | — |
| Fairway Medical Clinic | Houston | Texas | 77087 | — |
| 1960 Family Practice, PA | Houston | Texas | 77090 | — |
| Zion Urgent Care Clinic | Katy | Texas | 77494 | — |
| Family Practice Center | McAllen | Texas | 78501 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04828161, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04828161 live on ClinicalTrials.gov.