A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder
Public ClinicalTrials.gov record NCT04832425. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase 2/3 Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of PRAX-114 in Participants With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of PRAX-114 in participants with moderate to severe major depressive disorder (MDD). Participants will be randomized to receive 28 days of either 40 mg PRAX-114 or placebo in a 1:1 ratio.
Study identification
- NCT ID
- NCT04832425
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 216 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 30, 2021 (Actual)
- Primary completion
- May 5, 2022 (Actual)
- Completion
- May 5, 2022 (Actual)
- Last update posted
- Jul 21, 2022
2021 – 2022
United States locations
- U.S. sites
- 30
- U.S. states
- 17
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Praxis Research Site | Phoenix | Arizona | 85012 | — |
| Praxis Research Site | Garden Grove | California | 92845 | — |
| Praxis Research Site | Lafayette | California | 94549 | — |
| Praxis Research Site | Lemon Grove | California | 91945 | — |
| Praxis Research Site | Oceanside | California | 92056 | — |
| Praxis Research Site | Pico Rivera | California | 90660 | — |
| Praxis Research Site | Redlands | California | 92374 | — |
| Praxis Research Site | Jacksonville | Florida | 32256 | — |
| Praxis Research Site | Orange City | Florida | 32763 | — |
| Praxis Research Site | Orlando | Florida | 32801 | — |
| Praxis Research Site | Atlanta | Georgia | 30331 | — |
| Praxis Research Site | Decatur | Georgia | 30030 | — |
| Praxis Research Site | Chicago | Illinois | 60076 | — |
| Praxis Research Site | Gaithersburg | Maryland | 20877 | — |
| Praxis Research Site | Worcester | Massachusetts | 01655 | — |
| Praxis Research Site | O'Fallon | Missouri | 63368 | — |
| Praxis Research Site | Las Vegas | Nevada | 89102 | — |
| Praxis Research Site | Berlin | New Jersey | 08009 | — |
| Praxis Research Site | Marlton | New Jersey | 08053 | — |
| Praxis Research Site | Cedarhurst | New York | 11516 | — |
| Praxis Research Site | Rochester | New York | 14618 | — |
| Praxis Research Site | Staten Island | New York | 10312 | — |
| Praxis Research Site | Dayton | Ohio | 45417 | — |
| Praxis Research Site | Allentown | Pennsylvania | 18104 | — |
| Praxis Research Site | Media | Pennsylvania | 19063 | — |
| Praxis Research Site | Memphis | Tennessee | 38119 | — |
| Praxis Research Site | Austin | Texas | 78737 | — |
| Praxis Research Site | San Antonio | Texas | 78229 | — |
| Praxis Research Site | Charlottesville | Virginia | 22903 | — |
| Praxis Research Site | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04832425, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 21, 2022 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04832425 live on ClinicalTrials.gov.