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Completed Phase 1 Interventional

A Study of Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma

ClinicalTrials.gov ID: NCT04833582

Public ClinicalTrials.gov record NCT04833582. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 17, 2026, 3:16 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Dose Escalation and Dose Expansion Study of ZN-c3 in Combination With Gemcitabine in Adult and Pediatric Subjects With Relapsed or Refractory Osteosarcoma

Study identification

NCT ID
NCT04833582
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Industry
Enrollment
31 participants

Conditions and interventions

Conditions

Interventions

  • Azenosertib Drug
  • Gemcitabine Drug

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2021
Primary completion
Aug 29, 2023
Completion
Mar 29, 2024
Last update posted
Apr 2, 2026

2021 – 2024

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Site 0106 Los Angeles California 90095
Site 0124 Oakland California 94609
Site 0195 Santa Monica California 90403
University of Florida College of Medicine Gainesville Florida 32610
Site 0105 New York New York 10065
Site 0107 Cincinnati Ohio 45229
Site 0123 Portland Oregon 97239
Site 0193 Memphis Tennessee 38105
Site 0197 Nashville Tennessee 37332
Site 0103 Houston Texas 77030
Site 0188 Richmond Virginia 23298
Site 0122 Seattle Washington 98195

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04833582, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 2, 2026 · Synced May 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04833582 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →