Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-2)
Public ClinicalTrials.gov record NCT04846881. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized, Double-blind, Placebo-controlled, Parallel Group Trial to Examine the Efficacy and Safety of Iclepertin Once Daily Over 26 Week Treatment Period in Patients With Schizophrenia (CONNEX-2)
Study identification
- NCT ID
- NCT04846881
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Boehringer Ingelheim
- Industry
- Enrollment
- 611 participants
Conditions and interventions
Conditions
Interventions
- Iclepertin Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2021
- Primary completion
- Oct 17, 2024
- Completion
- Nov 16, 2024
- Last update posted
- Dec 11, 2025
2021 – 2024
United States locations
- U.S. sites
- 20
- U.S. states
- 11
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Innovations, Inc | Bellflower | California | 90706 | — |
| ATP Clinical Research, Inc. | Costa Mesa | California | 92626 | — |
| ASCLEPES Research Centers, P.C. dba Alliance Research | Long Beach | California | 90807 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| NRC Research Institute | Orange | California | 92868 | — |
| Collaborative Neuroscience Research, LLC-Torrance-69527 | Torrance | California | 90504 | — |
| Connecticut Mental Health Center | New Haven | Connecticut | 06519 | — |
| Research in Miami Inc | Hialeah | Florida | 33013 | — |
| Optimus U Corporation-Miami-69452 | Miami | Florida | 33135 | — |
| Health Synergy Clinical Research, LLC | West Palm Beach | Florida | 33407 | — |
| American Medical Research | Chicago | Illinois | 60612 | — |
| Sheppard Pratt Physicians's Practice Association, Inc. | Baltimore | Maryland | 21204 | — |
| PsychCare Consultants Research | St Louis | Missouri | 63128 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | — |
| New York State Psychiatric Institute | New York | New York | 10032 | — |
| Insight Clinical Trials, LLC, Independence | Independence | Ohio | 44131 | — |
| Relaro Medical Trials, LLC | Dallas | Texas | 75243 | — |
| John Peter Smith Health Network | Fort Worth | Texas | 76104 | — |
| Salem VA Medical Center | Salem | Virginia | 24153 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 107 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04846881, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 11, 2025 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04846881 live on ClinicalTrials.gov.