A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
Public ClinicalTrials.gov record NCT04847557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study Comparing the Efficacy and Safety of Tirzepatide Versus Placebo in Patients With Heart Failure With Preserved Ejection Fraction and Obesity (SUMMIT)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to assess the efficacy and safety of Tirzepatide (LY3298176) in participants with heart failure with preserved ejection fraction and obesity.
Study identification
- NCT ID
- NCT04847557
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 731 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 20, 2021 (Actual)
- Primary completion
- Jul 2, 2024 (Actual)
- Completion
- Jul 2, 2024 (Actual)
- Last update posted
- Aug 20, 2025
2021 – 2024
United States locations
- U.S. sites
- 54
- U.S. states
- 29
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research | Huntsville | Alabama | 35801 | — |
| Westside Medical Associates of Los Angeles | Beverly Hills | California | 90211 | — |
| Valley Clinical Trials, Inc. | Covina | California | 91723 | — |
| Amicis Research Center | Granada Hills | California | 91344 | — |
| University of California San Diego - La Jolla | La Jolla | California | 92037 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| The Lundquist Institute | Torrance | California | 90502 | — |
| South Denver Cardiology Associates | Littleton | Colorado | 80120 | — |
| Cardiology Associates of Fairfield County, P.C. | Stamford | Connecticut | 06905 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| Clearwater Cardiovascular & Interventional Consultants M.D., P.A. | Clearwater | Florida | 33756 | — |
| Clearwater Cardiovascular & Interventional Consultants M.D., P.A. | Largo | Florida | 33777 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| Ocala Caridovascular Research | Ocala | Florida | 34471 | — |
| Clearwater Cardiovascular & Interventional Consultants M.D., P.A. | Safety Harbor | Florida | 34695 | — |
| East Coast Institute for Research - St. Augustine | Saint Augustine | Florida | 32086 | — |
| Morehouse School Of Medicine | Atlanta | Georgia | 30310 | — |
| St. Luke's Boise Medical Center | Boise | Idaho | 83712 | — |
| Northwest Heart Clinical Research | Arlington Heights | Illinois | 60005 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| Cardiovascular Research of Northwest Indiana | Munster | Indiana | 46321 | — |
| Midwest Heart & Vascular Specialists | Overland Park | Kansas | 66211 | — |
| Grace Research - Bossier | Bossier City | Louisiana | 71111 | — |
| The Heart Clinic - Hammond | Hammond | Louisiana | 70403 | — |
| Grace Research - Shreveport | Shreveport | Louisiana | 71105 | — |
| Maryland Cardiovascular Specialists | Baltimore | Maryland | 21229 | — |
| McLaren Bay Region | Bay City | Michigan | 48708 | — |
| St. Louis Heart and Vascular, P.C. | St Louis | Missouri | 63136 | — |
| Palm Research Center Tenaya | Las Vegas | Nevada | 89128 | — |
| The Heart House | Haddon Heights | New Jersey | 08035 | — |
| Lovelace Medical Center | Albuquerque | New Mexico | 87102 | — |
| Erie County Medical Center | Buffalo | New York | 14215 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Saratoga Cardiology Associates | Saratoga Springs | New York | 12866 | — |
| Stony Brook University | Stony Brook | New York | 11794 | — |
| OnSite Clinical Solutions | Charlotte | North Carolina | 28277 | — |
| Aultman Hospital Research | Canton | Ohio | 44710 | — |
| Rama Research | Marion | Ohio | 43302 | — |
| Hightower Clinical Trial Services | Oklahoma City | Oklahoma | 73102 | — |
| Hillsboro Cardiology | Hillsboro | Oregon | 97123 | — |
| Capital Area Research, LLC | Camp Hill | Pennsylvania | 17011 | — |
| Doylestown Hospital | Doylestown | Pennsylvania | 18901 | — |
| UPMC Clinical Trials | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Monument Health Rapid City Hospital | Rapid City | South Dakota | 57701 | — |
| The Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | — |
| Apex Research Foundation | Jackson | Tennessee | 38301 | — |
| DiscoveResearch | Beaumont | Texas | 77701 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| North Dallas Research Associates | McKinney | Texas | 75069 | — |
| Sherman Clinical Research | Sherman | Texas | 75092 | — |
| Northwest Houston Heart Center | Tomball | Texas | 77375 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| MultiCare Good Samaritan Hospital | Puyallup | Washington | 98372 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 92 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04847557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 20, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04847557 live on ClinicalTrials.gov.