Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer
Public ClinicalTrials.gov record NCT04849364. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer (PERSEVERE)
Study identification
- NCT ID
- NCT04849364
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Bryan Schneider, MD
- Other
- Enrollment
- 52 participants
Conditions and interventions
Conditions
Interventions
- Capecitabine Drug
- Talazoparib Drug
- Pembrolizumab Drug
- Inavolisib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2021
- Primary completion
- Oct 23, 2024
- Completion
- Dec 1, 2024
- Last update posted
- May 30, 2025
2021 – 2024
United States locations
- U.S. sites
- 13
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Georgetown University | Washington D.C. | District of Columbia | 20057 | — |
| Memorial Healthcare System | Hollywood | Florida | 33028 | — |
| Miami Cancer Institute at Baptist Health, Inc. | Miami | Florida | 33176 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Indianapolis | Indiana | 46202 | — |
| Summit Health | Berkeley Heights | New Jersey | 07922 | — |
| Novant Health Cancer Institute | Winston-Salem | North Carolina | 27103 | — |
| Mays Cancer Center at UT Health San Antonio | San Antonio | Texas | 78229 | — |
| University of Wisconsin | Madison | Wisconsin | 53705 | — |
| Froedtert and The Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Advocate Aurora Research Institute (Illinois) | Wauwatosa | Wisconsin | 53226 | — |
| Aurora Health Care | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04849364, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 30, 2025 · Synced Jun 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04849364 live on ClinicalTrials.gov.