Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis
Public ClinicalTrials.gov record NCT04851964. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis (WAYPOINT)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Multicentre, Randomised, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study of Tezepelumab in Participants with Severe Chronic Rhinosinusitis with Nasal Polyposis
Study identification
- NCT ID
- NCT04851964
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 416 participants
Conditions and interventions
Conditions
Interventions
- Experimental: Tezepelumab Biological
- Placebo Other
- Mometasone furoate or equivalent intranasal corticosteroid Drug
Biological · Other · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 22, 2021 (Actual)
- Primary completion
- Sep 23, 2024 (Actual)
- Completion
- Dec 11, 2024 (Actual)
- Last update posted
- Jan 27, 2026
2021 – 2024
United States locations
- U.S. sites
- 21
- U.S. states
- 16
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35209 | — |
| Research Site | Bakersfield | California | 93301 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Roseville | California | 95661 | — |
| Research Site | Walnut Creek | California | 94598 | — |
| Research Site | Colorado Springs | Colorado | 80923 | — |
| Research Site | Denver | Colorado | 80230 | — |
| Research Site | Boca Raton | Florida | 33487 | — |
| Research Site | Chicago | Illinois | 60657 | — |
| Research Site | Baltimore | Maryland | 21224 | — |
| Research Site | White Marsh | Maryland | 21162 | — |
| Research Site | Boston | Massachusetts | 02115 | — |
| Research Site | Columbia | Missouri | 65212 | — |
| Research Site | New York | New York | 10003 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Oklahoma City | Oklahoma | 73120 | — |
| Research Site | North Charleston | South Carolina | 29406 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Norfolk | Virginia | 23507 | — |
| Research Site | Spokane | Washington | 99201 | — |
| Research Site | Milwaukee | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 91 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04851964, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04851964 live on ClinicalTrials.gov.