A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
Public ClinicalTrials.gov record NCT04853251. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IV, Multicenter, Open-label Study to Assess Corneal Endothelial Cells in Patients With Neovascular Age-related Macular Degeneration Treated With the Port Delivery System With Ranibizumab (PDS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W).
Study identification
- NCT ID
- NCT04853251
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 188 participants
Conditions and interventions
Conditions
Interventions
Device · Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2021 (Actual)
- Primary completion
- Jul 30, 2027 (Estimated)
- Completion
- Aug 31, 2027 (Estimated)
- Last update posted
- Oct 2, 2026
2021 – 2027
United States locations
- U.S. sites
- 52
- U.S. states
- 28
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barnet Dulaney Perkins Eye Center | Mesa | Arizona | 85206-2747 | Active, not recruiting |
| California Retina Consultants | Bakersfield | California | 93309 | Completed |
| Retina Associates of Southern California | Huntington Beach | California | 92647 | Active, not recruiting |
| California Eye Specialists Medical group Inc. | Pasadena | California | 91107-3747 | Completed |
| Retinal Consultants Med Group | Sacramento | California | 95841-2013 | Active, not recruiting |
| University of California San Francisco | San Francisco | California | 94158-2510 | Active, not recruiting |
| Orange County Retina Med Group | Santa Ana | California | 92705-6504 | Active, not recruiting |
| Macula Retina Vitreous Research Institute | Torrance | California | 90503-3270 | Active, not recruiting |
| Southwest Retina Consultants | Durango | Colorado | 81303 | Completed |
| Advanced Vision Research Institute | Longmont | Colorado | 80503-6499 | Active, not recruiting |
| Retina Group of New England | Waterford | Connecticut | 06385-1215 | Withdrawn |
| Retina Specialty Institute | Pensacola | Florida | 32503-2030 | Active, not recruiting |
| Ft Lauderdale Eye Institute | Plantation | Florida | 33324-3118 | Withdrawn |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711-1141 | Active, not recruiting |
| Southeast Retina Center | Augusta | Georgia | 30909-6440 | Active, not recruiting |
| University Retina and Macula Associates, PC | Lemont | Illinois | 60439-7421 | Active, not recruiting |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | Withdrawn |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509-1827 | Withdrawn |
| Maine Eye Center | Portland | Maine | 04101 | Active, not recruiting |
| The Retina Care Center | Baltimore | Maryland | 21209-2219 | Active, not recruiting |
| Wilmer Eye Institute Johns Hopkins University | Baltimore | Maryland | 21287-0005 | Active, not recruiting |
| Retina Group of Washington | Chevy Chase | Maryland | 20815-6956 | Withdrawn |
| Cumberland Valley Retina Consultants PC | Hagerstown | Maryland | 21740 | Completed |
| Associated Retinal Consultants PC | Royal Oak | Michigan | 48073 | Active, not recruiting |
| VitreoRetinal Surgery, PLLC. | Minneapolis | Minnesota | 55435-3004 | Active, not recruiting |
| Midwest Vision Research Foundation | Chesterfield | Missouri | 63017-5065 | Completed |
| Sierra Eye Associates | Reno | Nevada | 89502-1605 | Active, not recruiting |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | Active, not recruiting |
| Seeta Eye Centers | Poughkeepsie | New York | 12603-2416 | Active, not recruiting |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803-2493 | Withdrawn |
| Duke Eye Center | Durham | North Carolina | 27705-4699 | Active, not recruiting |
| Graystone Eye-Hickory - 2415 Century Pl | Hickory | North Carolina | 28602 | Recruiting |
| Fargo Retina Consultants | Fargo | North Dakota | 58047 | Active, not recruiting |
| Cincinnati Eye Institute | Blue Ash | Ohio | 45242-5537 | Active, not recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Active, not recruiting |
| Tulsa Retina Consultants | Tulsa | Oklahoma | 74114 | Withdrawn |
| Erie Retina Research | Erie | Pennsylvania | 16505 | Completed |
| Mid Atlantic Retina | Philadelphia | Pennsylvania | 19107-5109 | Withdrawn |
| Palmetto Retina Center | Florence | South Carolina | 29501 | Withdrawn |
| Palmetto Retina Center, LLC | West Columbia | South Carolina | 29169-2429 | Withdrawn |
| Charles Retina Institute | Germantown | Tennessee | 38138-2405 | Active, not recruiting |
| Tennessee Retina PC | Nashville | Tennessee | 37203-1596 | Active, not recruiting |
| Panhandle Eye Group LLP Southwest Retina Specialists | Amarillo | Texas | 79106-1835 | Completed |
| Austin Retina Associates | Austin | Texas | 78705-1169 | Withdrawn |
| Austin Clinical Research, LLC | Austin | Texas | 78750-2298 | Recruiting |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | Active, not recruiting |
| Retina Consultants of Texas | Schertz | Texas | 78154 | Active, not recruiting |
| Retina Associates of Utah, PLLC | Salt Lake City | Utah | 84107-6767 | Active, not recruiting |
| Piedmont Eye Center | Lynchburg | Virginia | 24502-4271 | Active, not recruiting |
| Wagner Kapoor Institute | Norfolk | Virginia | 23502-3933 | Active, not recruiting |
| Retina Institute of Virginia | Richmond | Virginia | 23235-1962 | Withdrawn |
| Spokane Eye Clinical Research | Spokane | Washington | 99204-2509 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04853251, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 2, 2026 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04853251 live on ClinicalTrials.gov.