Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
Public ClinicalTrials.gov record NCT04854499. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goals of this clinical study are to learn about the safety, tolerability, dosing and effectiveness of the study drug, magrolimab in combination with other anticancer therapies in participants with head and neck squamous cell carcinoma (HNSCC).
Study identification
- NCT ID
- NCT04854499
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 193 participants
Conditions and interventions
Conditions
Interventions
- Magrolimab Drug
- Pembrolizumab Drug
- Docetaxel Drug
- 5-FU Drug
- Cisplatin Drug
- Carboplatin Drug
- Zimberelimab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 7, 2021 (Actual)
- Primary completion
- Oct 2, 2024 (Actual)
- Completion
- Oct 2, 2024 (Actual)
- Last update posted
- Nov 19, 2025
2021 – 2024
United States locations
- U.S. sites
- 22
- U.S. states
- 16
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ironwood Cancer and Research Center | Chandler | Arizona | 85224 | — |
| City of Hope | Duarte | California | 91010 | — |
| UCLA Hematology/Oncology | Los Angeles | California | 90095 | — |
| Stanford Cancer Institute | Palo Alto | California | 94305 | — |
| Torrance Memorial Physician Network - Cancer Care Associates | Redondo Beach | California | 90277 | — |
| Providence Medical Foundation | Santa Rosa | California | 95403 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Ocala Oncology Center | Ocala | Florida | 34471 | — |
| University Center and Blood Center,LLC. | Athens | Georgia | 30607 | — |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| Virginia Piper Cancer Center (Alliant Health | Minneapolis | Minnesota | 55407 | — |
| Washington University of Medicine- Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Astera Cancer Care | East Brunswick | New Jersey | 08816 | — |
| Icahn School of Medicine at Mount Sinai and the Mount Sinai Hospital | New York | New York | 10029 | — |
| New York Cancer and Blood Specialists | Port Jefferson Station | New York | 11776 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58122 | — |
| OU Health Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17602 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 66 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04854499, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2025 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04854499 live on ClinicalTrials.gov.