Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)
Public ClinicalTrials.gov record NCT04857996. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Prospective, Multicenter, Randomized, Double Masked, Sham-Controlled Study to Assess the Safety, Tolerability and Evidence of Activity of a Single Intravitreal Injection of UBX1325 in Patients With Diabetic Macular Edema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is intended to assess the exposure, safety, biological activity, and durability of UBX1325, a phosphate pro-drug, and its active parent molecule (UBX0601) following a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME).
Study identification
- NCT ID
- NCT04857996
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 25, 2021 (Actual)
- Primary completion
- Apr 6, 2023 (Actual)
- Completion
- Apr 6, 2023 (Actual)
- Last update posted
- May 16, 2024
2021 – 2023
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute, LLC | Phoenix | Arizona | 85053 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Salehi Retina Institute Inc. | Huntington Beach | California | 92647 | — |
| Loma Linda University | Loma Linda | California | 92354 | — |
| California Retina Consultants | Oxnard | California | 93036 | — |
| Advanced Vision Research Institute | Longmont | Colorado | 80503 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| MedEye Associates | Miami | Florida | 33143 | — |
| Northwestern Medical Group | Chicago | Illinois | 60611 | — |
| MidWest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Mass Eye and Ear Institute | Boston | Massachusetts | 02114 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| New York Eye and Ear Infirmary | New York | New York | 10003 | — |
| EyeHealth Northwest | Portland | Oregon | 97225 | — |
| Retina Consultants of Carolina, PA | Greenville | South Carolina | 29605 | — |
| Valley Retina Institute, P.A. | McAllen | Texas | 78503 | — |
| Retina Center of Texas | Southlake | Texas | 76092 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04857996, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 16, 2024 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04857996 live on ClinicalTrials.gov.