Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
Public ClinicalTrials.gov record NCT04862468. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT (DEXTERITY-AFP)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study of a medical procedure that utilizes a commercially available catheter (the Bullfrog® Micro-Infusion Device) to locally deliver a commercially available anti-inflammatory drug (dexamethasone sodium phosphate injection) around the deep veins after DVT recanalization, where DVT symptoms were present for up to 14 days prior to recanalization. The goal of the study is to see if local anti-inflammation helps prevent re-thrombosis of the blood vessel and improvement in symptoms for up to 24 months after the initial DVT recanalization procedure.
Study identification
- NCT ID
- NCT04862468
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 80 participants
Conditions and interventions
Conditions
Interventions
- Perivascular dexamethasone Combination Product
- Perivascular sham Combination Product
Combination Product
Eligibility (public fields only)
- Age range
- 18 Years to 89 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 28, 2021
- Primary completion
- Jul 31, 2026
- Completion
- Jan 31, 2028
- Last update posted
- Jul 3, 2025
2021 – 2028
United States locations
- U.S. sites
- 15
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence St. Joseph Hospital | Orange | California | 92868 | Recruiting |
| Vascular Care Connecticut | Darien | Connecticut | 06820 | Recruiting |
| HCA Florida JFK Hospital | Atlantis | Florida | 33462 | Recruiting |
| Baptist Health | Jacksonville | Florida | 32258 | Recruiting |
| University of South Florida | Tampa | Florida | 33060 | Recruiting |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | Recruiting |
| CIS Clinical Research | Houma | Louisiana | 70360 | Recruiting |
| Medstar Health Research Institute | Hyattsville | Maryland | 20782 | Recruiting |
| Englewood Health | Englewood | New Jersey | 07631 | Recruiting |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | Recruiting |
| NC Heart and Vascular Research | Raleigh | North Carolina | 27607 | Recruiting |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | Active, not recruiting |
| St John Health System | Bartlesville | Oklahoma | 74006 | Active, not recruiting |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | Recruiting |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23452 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04862468, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 3, 2025 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04862468 live on ClinicalTrials.gov.