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Terminated Phase 2 Interventional Results available

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Docetaxel for Metastatic Non-Small Cell Lung Cancer (NSCLC) (PRESERVE 4)

ClinicalTrials.gov ID: NCT04863248

Public ClinicalTrials.gov record NCT04863248. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 5:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Double-blind, Clinical Trial of Trilaciclib Versus Placebo in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) Treated With Docetaxel in the 2nd/3rd Line Setting (PRESERVE 4)

Study identification

NCT ID
NCT04863248
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
G1 Therapeutics, Inc.
Industry
Enrollment
10 participants

Conditions and interventions

Interventions

  • Trilaciclib Drug
  • Placebo Drug
  • Docetaxel Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 29, 2021
Primary completion
Feb 1, 2022
Completion
Feb 1, 2022
Last update posted
Apr 13, 2023

2021 – 2022

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Ironwood Cancer & Research Centers Phoenix Arizona 85028
Valkyrie Clinical Trials Los Angeles California 90067
Desert Hematology Oncology Medical Group, Inc Rancho Mirage California 92270
Innovative Clinical Research Institute - Oncology Whittier California 90602
Mid-Florida Hematology Oncology Orange City Florida 32763
Indiana University Health Goshen Cancer Center Goshen Indiana 46526
St. Louis Cancer Care, LLP Bridgeton Missouri 63044
Summit Medical Group Florham Park New Jersey 07932
Regional Cancer Car Associates, LLC Little Silver New Jersey 07739
Gettysburg Cancer Center Gettysburg Pennsylvania 17325
University of Tennessee Medical Center Knoxville Tennessee 37920
Millennium Oncology Houston Texas 77090

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04863248, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 13, 2023 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04863248 live on ClinicalTrials.gov.

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