Study of Efficacy, Safety, and Tolerability of LNA043 in Patients With Knee Osteoarthritis
Public ClinicalTrials.gov record NCT04864392. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 5-year, Randomized, Double-blind, Placebo-controlled, Multi-center Study Assessing the Efficacy, Safety, and Tolerability of Intra-articular Regimens of LNA043 Versus Placebo in Patients With Symptomatic Knee Osteoarthritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was a multicenter, randomized, double-blind, placebo-controlled Phase IIb study evaluating intra-articular LNA043 in patients with knee osteoarthritis.
Study identification
- NCT ID
- NCT04864392
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 576 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2021 (Actual)
- Primary completion
- Sep 29, 2024 (Actual)
- Completion
- May 29, 2025 (Actual)
- Last update posted
- Apr 2, 2026
2021 – 2025
United States locations
- U.S. sites
- 23
- U.S. states
- 12
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Tucson Orthopedic Institute PC | Tucson | Arizona | 85712 | — |
| Sharps Hospital Grossmont | La Mesa | California | 91942 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| Long Beach Clinical Trials | Long Beach | California | 90806 | — |
| Artemis Institute Clinical Research | Riverside | California | 92503 | — |
| Northern California Research | Sacramento | California | 95821 | — |
| Arthemis Clinical Research | San Diego | California | 92103 | — |
| Stamford Therapeutics Consortium LLC | Stamford | Connecticut | 06905 | — |
| Sensible Healthcare | Ocoee | Florida | 34761 | — |
| Clinical Research of West Florida Inc | Tampa | Florida | 33603 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Chicago Clinical Research Inst | Chicago | Illinois | 60607 | — |
| Tandem clinical research | Marrero | Louisiana | 70072 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Center For Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| AMR Knoxville | Knoxville | Tennessee | 37920 | — |
| Metroplex Clinical Research | Dallas | Texas | 75231 | — |
| Pioneer Research Solutions | Sugar Land | Texas | 77479 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Annapolis Rheumatology LLC | Fairfax | Virginia | 22033 | — |
| Virginia Ispine Physicians PC | Richmond | Virginia | 23238 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04864392, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04864392 live on ClinicalTrials.gov.