A Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With an Extension
Public ClinicalTrials.gov record NCT04880031. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Blinded, Placebo-controlled Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With a Single Arm Open-label Extension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, blinded, placebo-controlled study of Efimosfermin in obese participants at risk for, or with biopsy-confirmed, nonalcoholic steatohepatitis (NASH), with a single arm open-label extension. It includes Parts A, B, C and D.
Study identification
- NCT ID
- NCT04880031
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 231 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2021 (Actual)
- Primary completion
- Oct 27, 2025 (Actual)
- Completion
- Oct 27, 2025 (Actual)
- Last update posted
- Jul 8, 2026
2021 – 2025
United States locations
- U.S. sites
- 48
- U.S. states
- 12
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Research Associates | Birmingham | Alabama | 35205 | — |
| Arizona Liver Health | Chandler | Arizona | 85224 | — |
| Arizona Liver Health | Peoria | Arizona | 85381 | — |
| Arizona Liver Health | Tucson | Arizona | 85712 | — |
| Liver Institute PPLC | Tucson | Arizona | 85712 | — |
| QLMC | Tucson | Arizona | 85712 | — |
| Alliance Research Institute | Canoga Park | California | 91304 | — |
| Ark Clinical Research | Fountain Valley | California | 92708 | — |
| Fresno Clinical Research Center | Fresno | California | 92720 | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| Knowledge Research Center | Orange | California | 92868 | — |
| FOMAT Medical Research | Oxnard | California | 93030 | — |
| Inland Empire Clinical Trials | Rialto | California | 92377 | — |
| Southwest General Healthcare Center | Fort Myers | Florida | 33907 | — |
| Covenant Metabolic Specialists - Fort Myers | Fort Myers | Florida | 33912 | — |
| Evolution Clinical Trials | Hialeah Gardens | Florida | 33016 | — |
| Entrust Clinical Research Center | Kendall | Florida | 33176 | — |
| Galenus Group | Lehigh Acres | Florida | 33976 | — |
| G+C Research Group | Miami | Florida | 33126 | — |
| Miami Clinical Research | Miami | Florida | 33155 | — |
| Advanced Clinical Research | Miami | Florida | 33156 | — |
| Admed Research | Miami | Florida | 33173 | — |
| Century Research | Miami | Florida | 33173 | — |
| Panex Clinical Research | Miami Lakes | Florida | 33014 | — |
| Charter Research | Orlando | Florida | 32803 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Covenant Metabolic Specialists - Sarasota | Sarasota | Florida | 34240 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Coastal Research Institute, LLC | Fayetteville | North Carolina | 28304 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| Velocity Clinical Research | East Greenwich | Rhode Island | 02818 | — |
| Accelemed Research | Austin | Texas | 78745 | — |
| Pinnacle Clinical Research - Austin | Austin | Texas | 78757 | — |
| Texas Liver Institute - Austin | Austin | Texas | 78757 | — |
| Apex Mobile Clinical Research | Bellaire | Texas | 77401 | — |
| South Texas Research Institute-Brownsville | Brownsville | Texas | 78520 | — |
| South Texas Research Institute-Edinburg | Edinburg | Texas | 75839 | — |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | — |
| Houston Research Institute | Houston | Texas | 77079 | — |
| LinQ Research, LLC | Pearland | Texas | 77584 | — |
| Quality Research, Inc | San Antonio | Texas | 78209 | — |
| American Research Corporation at Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Pinnacle Clinical Research - San Antonio | San Antonio | Texas | 78229 | — |
| Velocity Clinical Research - Waco | Waco | Texas | 76710 | — |
| Olympus Family Medicine | Salt Lake City | Utah | 84117 | — |
| South Ogden Family Medicine | South Ogden | Utah | 84405 | — |
| Liver Institute NorthWest | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04880031, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04880031 live on ClinicalTrials.gov.