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Completed Phase 1Phase 2 Interventional

Study Of ATRN-119 In Patients With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT04905914

Public ClinicalTrials.gov record NCT04905914. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2a, Open-Label, Safety, Pharmacokinetic, And Preliminary Efficacy Study Of Oral ATRN-119 In Patients With Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the safety and effectiveness of ATRN-119 through the performance of a Phase 1/2a, open-label, safety, PK, and preliminary efficacy study of oral ATRN-119 in patients with advanced solid tumors.

Study identification

NCT ID
NCT04905914
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Aprea Therapeutics
Industry
Enrollment
43 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 8, 2023
Primary completion
Mar 8, 2026
Completion
Mar 8, 2026
Last update posted
Aug 3, 2026

2023 – 2026

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
7
Facility City State ZIP Site status
Yale Cancer Center New Haven Connecticut 06520-8028
University Hospitals, Cleveland Medical Center Cleveland Ohio 44106
Jordan Center for Gynecologic Oncology at Penn Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104
Mary Crowley Cancer Research Dallas Texas 75230
NEXT- Oncology Dallas Irving Texas 75039
NEXT Oncology- San Antonio San Antonio Texas 78229
NEXT Oncology- Virginia Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04905914, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 3, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04905914 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →