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Active, not recruiting Phase 3 Interventional Results available

A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate

ClinicalTrials.gov ID: NCT04909801

Public ClinicalTrials.gov record NCT04909801. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 11:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatment With Subcutaneous Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive Rheumatoid Arthritis Who Have "Shared Epitope" HLA Class II Risk Alleles and Have an Inadequate Response to Methotrexate

Study identification

NCT ID
NCT04909801
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
338 participants

Conditions and interventions

Interventions

  • Abatacept Drug
  • Adalimumab Drug
  • Methotrexate Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 14, 2021
Primary completion
Jun 13, 2023
Completion
Aug 31, 2027
Last update posted
Feb 18, 2025

2021 – 2027

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
Local Institution - 0036 Fullerton California 92835
Local Institution - 0086 Los Alamitos California 90720
Local Institution - 0041 Aurora Colorado 80045
Local Institution - 0058 Cumberland Maryland 21502
Local Institution - 0038 Hagerstown Maryland 21740
Local Institution - 0084 Eagan Minnesota 55121
Local Institution - 0040 Freehold New Jersey 07728
NYU Langone Ambulatory Care Brooklyn Heights Brooklyn New York 11201
Local Institution - 0082 Wilmington North Carolina 28401
Local Institution - 0127 Portland Oregon 97239
Local Institution - 0031 Duncansville Pennsylvania 16635
Local Institution - 0034 Jackson Tennessee 38305
Local Institution - 0044 Dallas Texas 75231
Local Institution - 0119 Milwaukee Wisconsin 53217

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 61 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04909801, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 18, 2025 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04909801 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →