DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Public ClinicalTrials.gov record NCT04920617. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Open-label, Multicenter, Randomized Parallel-Group, Two-Stage, Study of an Immunotherapeutic Treatment DPX-Survivac and Pembrolizumab, With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (VITALIZE)
Study identification
- NCT ID
- NCT04920617
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- ImmunoVaccine Technologies, Inc. (IMV Inc.)
- Industry
- Enrollment
- 102 participants
Conditions and interventions
Interventions
- DPX-Survivac Drug
- Pembrolizumab Drug
- CPA Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 17, 2021
- Primary completion
- Sep 30, 2024
- Completion
- Mar 31, 2025
- Last update posted
- Apr 6, 2023
2021 – 2025
United States locations
- U.S. sites
- 17
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Compassionate Cancer Care Medical Group | Fountain Valley | California | 92708 | Recruiting |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | Withdrawn |
| BRCR Medical Center Inc. | Hollywood | Florida | 33021 | Withdrawn |
| BRCR Medical Center Inc. | Plantation | Florida | 33322 | Withdrawn |
| Comprehensive Hematology and Oncology | St. Petersburg | Florida | 33709 | Withdrawn |
| Blood and Marrow Transplant Group of Georgia | Atlanta | Georgia | 30342 | Recruiting |
| Indiana University Health Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | Recruiting |
| Tulane Cancer Center Office of Clinical Research | New Orleans | Louisiana | 70112 | Recruiting |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | Recruiting |
| Christus St. Vincent Regional Cancer Center | Santa Fe | New Mexico | 87505 | Recruiting |
| Brody School of Medicine at East Carolina University | Greenville | North Carolina | 27834 | Recruiting |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | Withdrawn |
| University of Toledo Medical Center | Toledo | Ohio | 43614 | Withdrawn |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | Recruiting |
| Allegheny Health Network (AHN) West Penn Hospital | Pittsburgh | Pennsylvania | 15224 | Recruiting |
| Reading Hospital - McGlinn Cancer Institute | West Reading | Pennsylvania | 19611 | Recruiting |
| Prairie Lakes Health Care System | Watertown | South Dakota | 57201 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04920617, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 6, 2023 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04920617 live on ClinicalTrials.gov.