Four-week Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in the Treatment of Narcolepsy
Public ClinicalTrials.gov record NCT04923594. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Four-week, Double-blind, Placebo-controlled, Randomized, Multicenter, Parallel-group Study of the Safety and Efficacy of NLS-2 (Mazindol Extended Release) in Adults for the Treatment of Narcolepsy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a double-blind, randomized, placebo-controlled, multicenter trial of NLS-2 in adult patients with narcolepsy. The study will enroll approximately 60 patients and eligible patients will be treated to receive either NLS-2 or placebo for 4-weeks.
Study identification
- NCT ID
- NCT04923594
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 67 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 13, 2021 (Actual)
- Primary completion
- Jun 30, 2022 (Actual)
- Completion
- Jun 30, 2022 (Actual)
- Last update posted
- Aug 12, 2022
2021 – 2022
United States locations
- U.S. sites
- 22
- U.S. states
- 12
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sleep Disorders Center of Alabama | Birmingham | Alabama | 35213 | — |
| Stanford Sleep Medicine Center | Redwood City | California | 94063 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| St. Francis Sleep Allergy and Lung Institute | Clearwater | Florida | 33765 | — |
| Sleep Medicine Specialists of South Florida | Miami | Florida | 33126 | — |
| Ivetmar Medical Group | Miami | Florida | 33155 | — |
| The Angel Medical Research Corporation | Miami Lakes | Florida | 33016 | — |
| Treken Primary care | Atlanta | Georgia | 30315 | — |
| NeuroTrials Research | Atlanta | Georgia | 30328 | — |
| Clinical Research Institute | Stockbridge | Georgia | 30281 | — |
| Hawaii Pacific Neuroscience Clinical Research Center | Honolulu | Hawaii | 96817 | — |
| The Center For Sleep & Wake Disorders | Chevy Chase | Maryland | 20815 | — |
| Sleep and Attention Disorders | Sterling Heights | Michigan | 48314 | — |
| Neurology and Sleep Disorders Clinic | Columbia | Missouri | 65212 | — |
| Carolinas Sleep Specialists | Concord | North Carolina | 28025 | — |
| Superior Clinical Research, LLC | Goldsboro | North Carolina | 27534 | — |
| Advanced Respiratory and Sleep Medicine | Huntersville | North Carolina | 28078 | — |
| Intrepid Research | Cincinnati | Ohio | 45245 | — |
| Ohio Sleep Medicine Institute | Dublin | Ohio | 43017 | — |
| Bogan Sleep Consultants | Columbia | South Carolina | 29201 | — |
| Dharma PA d/b/a Southwest Family Medicine Associates | Dallas | Texas | 75235 | — |
| Sleep Therapy & Research Center | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04923594, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 12, 2022 · Synced Nov 8, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04923594 live on ClinicalTrials.gov.