A Study to Evaluate the Immunogenicity and Safety of mRNA Vaccine Boosters for SARS-CoV-2 (COVID-19) Variants
Public ClinicalTrials.gov record NCT04927065. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Study to Evaluate the Immunogenicity and Safety of mRNA Vaccine Boosters for SARS-CoV-2 Variants
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1273.211, mRNA-1273, mRNA-1273.617.2, mRNA-1273.213, mRNA-1273.529, mRNA-1273.214, mRNA-1273.222, mRNA-1273.815, and mRNA-1273.231 administered as booster doses.
Study identification
- NCT ID
- NCT04927065
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 5,161 participants
Conditions and interventions
Conditions
Interventions
- mRNA-1273.211 Biological
- mRNA-1273 Biological
- mRNA-1273.617.2 Biological
- mRNA-1273.213 Biological
- mRNA-1273.529 Biological
- mRNA-1273.214 Biological
- mRNA-1273.222 Biological
- mRNA-1273.815 Biological
- mRNA-1273.231 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 28, 2021 (Actual)
- Primary completion
- Nov 17, 2023 (Actual)
- Completion
- Nov 17, 2023 (Actual)
- Last update posted
- Feb 28, 2025
2021 – 2023
United States locations
- U.S. sites
- 23
- U.S. states
- 14
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Benchmark Research (California) | Sacramento | California | 95864 | — |
| Research Centers of America | Hollywood | Florida | 33024 | — |
| Jacksonville Center For Clinical Research | Jacksonville | Florida | 32216 | — |
| Meridian Clinical Research-(Savannah Georgia) | Savannah | Georgia | 31406 | — |
| Meridian Clinical Research (Iowa) | Sioux City | Iowa | 51106 | — |
| Johnson County Clinical Trials | Lenexa | Kansas | 66219 | — |
| Meridian Clinical Research-(Baton Rouge, Louisiana) | Baton Rouge | Louisiana | 70809 | — |
| Benchmark Research | Metairie | Louisiana | 70006 | — |
| Meridian Clinical Research-(Rockville Maryland) | Rockville | Maryland | 20854 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Washington State University | St Louis | Missouri | 63110 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Meridian Clinical Research (Grand Island, Nebraska) | Grand Island | Nebraska | 68803 | — |
| Meridian Clinical Research (Norfolk-Nebraska) | Norfolk | Nebraska | 68701 | — |
| Meridian Clinical Research-(Omaha Nebraska) | Omaha | Nebraska | 68134 | — |
| Meridian Clinical Research, LLC | New York | New York | 13901 | — |
| Trial Management Associates | Wilmington | North Carolina | 28403 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Benchmark Research - Austin - HyperCore | Austin | Texas | 78705 | — |
| Tekton Research, Inc. | Austin | Texas | 78745 | — |
| Benchmark Research - Fort Worth - HyperCore | Fort Worth | Texas | 76135 | — |
| Texas Center for Drug Development, Inc. | Houston | Texas | 77081 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04927065, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 28, 2025 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04927065 live on ClinicalTrials.gov.