Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD
Public ClinicalTrials.gov record NCT04930445. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open Label, Observational, Prospective Registry of Participants With Sickle Cell Disease (SCD) Treated With Oxbryta® (Voxelotor)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This registry is an observational study designed to evaluate the effect of Oxbryta in individuals with SCD in a real-world setting.
Study identification
- NCT ID
- NCT04930445
- Recruitment status
- Terminated
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 265 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 4 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 3, 2022
- Primary completion
- Oct 9, 2024
- Completion
- Oct 9, 2024
- Last update posted
- Dec 30, 2025
2022 – 2024
United States locations
- U.S. sites
- 43
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama | Mobile | Alabama | 36617 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| University of California, San Diego | La Jolla | California | 92093-0987 | — |
| Center for Inherited Blood Disorders | Orange | California | 92868 | — |
| Bass Center for Childhood Cancer and Blood Disorders (Stanford Lucile Packard Children's Hospital) | Palo Alto | California | 94304 | — |
| Department of Pediatrics, Hematology section | Palo Alto | California | 94304 | — |
| Stanford Children's Hospital | Palo Alto | California | 94304 | — |
| University of Connecticut Health | Farmington | Connecticut | 06030-1163 | — |
| University of Connecticut Health | Farmington | Connecticut | 06030 | — |
| Nemours Alfred I duPont Hospital for Children | Wilmington | Delaware | 19803 | — |
| Nemours Children's Health, Wilmington | Wilmington | Delaware | 19803 | — |
| Foundation for Sickle Cell Disease Research | Hollywood | Florida | 33023 | — |
| Nemours Children's Specialty Care | Jacksonville | Florida | 32207 | — |
| University of Miami Hospital | Miami | Florida | 33136 | — |
| Augusta University - Clinical Trials Office (clinic) | Augusta | Georgia | 30912 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| University of Illinois at Chicago (UIC) Clinical Research Center | Chicago | Illinois | 60612 | — |
| University of Illinois at Chicago (UIC) Sickle Cell Center | Chicago | Illinois | 60612 | — |
| University of Illinois Hospital and Health Sciences System(UI Health) | Chicago | Illinois | 60612 | — |
| University of Illinois Hospital and Health Sciences System | Chicago | Illinois | 60612 | — |
| University of Maryland Medical Center | College Park | Maryland | 21201 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Mississippi Center for Advanced Medicine | Madison | Mississippi | 39110 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | — |
| Duke University Hospital | Durham | North Carolina | 27710 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| East Carolina University | Greenville | North Carolina | 27834-4300 | — |
| ECU Health Medical Center Laboratory | Greenville | North Carolina | 27834 | — |
| ECU Health Medical Center | Greenville | North Carolina | 27834 | — |
| UPMC Montefiore Hospital | Pittsburgh | Pennsylvania | 14213 | — |
| UPMC Sickle Cell Center | Pittsburgh | Pennsylvania | 15123 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | Pennsylvania | 15261 | — |
| Medical University of South Carolina Shawn Jenkins Women's and Children's Hospital | Charleston | South Carolina | 29425 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Children's Blood and Cancer Center at Dell Children's Medical Center | Austin | Texas | 78723 | — |
| Dell Children's Medical Center | Austin | Texas | 78723 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| INOVA Health | Falls Church | Virginia | 22042-2325 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04930445, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2025 · Synced Sep 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04930445 live on ClinicalTrials.gov.