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Completed Phase 3 Interventional

Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx

ClinicalTrials.gov ID: NCT04935177

Public ClinicalTrials.gov record NCT04935177. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 18, 2026, 12:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Controlled, Randomized Phase 3 Trial Evaluating 12-month Kidney Function in Highly Sensitized (cPRA ≥99.9%) Kidney Tx Patients With Positive XM Against a Deceased Donor, Comparing Desensitization Using Imlifidase With SoC

Study identification

NCT ID
NCT04935177
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hansa Biopharma AB
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

  • Anti-CD20 antibodies Drug
  • Eculizumab Drug
  • IVIg Drug
  • Imlifidase Drug
  • PLEX Procedure
  • Remain on wait list Other

Drug · Procedure · Other

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 13, 2021
Primary completion
Jun 19, 2025
Completion
Jun 19, 2025
Last update posted
Apr 29, 2026

2021 – 2025

United States locations

U.S. sites
25
U.S. states
16
U.S. cities
19
Facility City State ZIP Site status
University of Alabama at Birmingham (UAB) Hospital Birmingham Alabama 35249
Banner Health - University Medical Center - Phoenix Phoenix Arizona 85006
Mayo Clinic Phoenix Phoenix Arizona 85054
Keck Hospital of University of Southern California (USC) Los Angeles California 90033
Cedars-Sinai Medical Center Los Angeles California 90048
Sutter Health - California Pacific Medical Center San Francisco California 94115
University of California San Francisco (UCSF) Medical Center San Francisco California 94143-0780
Georgetown Transplant Institute Washington D.C. District of Columbia 20007
Northwestern University Chicago Illinois 60611
University of Chicago Medical Center Chicago Illinois 60637
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
John Hopkins Hospital Baltimore Maryland 21287
Massachusetts General Hospital Boston Massachusetts 02114
University of Minnesota Medical School Minneapolis Minnesota 55455
Mayo Clinic Rochester Rochester Minnesota 55905
Washington University School of Medicine St Louis Missouri 63110
Saint Barnabas Medical Center Livingston New Jersey 07039
New York University (NYU) Langone Transplant Institute, NYU Langone Health New York New York 10016
Columbia University New York New York 10032
New York-Presbyterian - Weill Cornell Medical Center New York New York 10065
Hospital of the University of Pennsylvania, Penn Medicine Philadelphia Pennsylvania 19104
Houston Methodist Hospital Houston Texas 77030
Methodist Hospital Specialty and Transplant San Antonio Texas 78229
University of Washington Medical Center Seattle Washington 98195
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04935177, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 29, 2026 · Synced May 18, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04935177 live on ClinicalTrials.gov.

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