A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension
Public ClinicalTrials.gov record NCT04936035. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-Controlled, Dose-Ranging Multicenter Study to Evaluate the Efficacy and Safety of ALN-AGT01 in Patients With Mild-to-Moderate Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect of ALN-AGT01 on systolic and diastolic blood pressure and to characterize the pharmacodynamic (PD) effects and safety of ALN-AGT01.
Study identification
- NCT ID
- NCT04936035
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 394 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 7, 2021 (Actual)
- Primary completion
- Apr 4, 2023 (Actual)
- Completion
- Dec 5, 2024 (Actual)
- Last update posted
- Dec 23, 2025
2021 – 2024
United States locations
- U.S. sites
- 54
- U.S. states
- 21
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Trial Site | Birmingham | Alabama | 35209 | — |
| Clinical Trial Site | Tempe | Arizona | 85281 | — |
| Clinical Trial Site | Tempe | Arizona | 85282 | — |
| Clinical Trial Site | Beverly Hills | California | 90211 | — |
| Clinical Trial Site | La Mesa | California | 91942 | — |
| Clinical Trial Site | Los Angeles | California | 90057 | — |
| Clinical Trial Site | San Diego | California | 92103 | — |
| Clinical Trial Site | South Gate | California | 90280 | — |
| Clinical Trial Site | Vista | California | 92083 | — |
| Clinical Trial Site | Washington D.C. | District of Columbia | 20011 | — |
| Clinical Trial Site | Clearwater | Florida | 33756 | — |
| Clinical Trial Site | Coral Gables | Florida | 33134 | — |
| Clinical Trial Site | Fleming Island | Florida | 32003 | — |
| Clinical Trial Site | Hollywood | Florida | 33021 | — |
| Clinical Trial Site | Hollywood | Florida | 33024 | — |
| Clinical Trial Site | Inverness | Florida | 34452 | — |
| Clinical Trial Site | Jacksonville | Florida | 32204 | — |
| Clinical Trial Site | Jacksonville | Florida | 32216 | — |
| Clinical Trial Site | Jacksonville | Florida | 32256 | — |
| Clinical Trial Site | Miami | Florida | 33126 | — |
| Clinical Trial Site | Miami | Florida | 33135 | — |
| Clinical Trial Site | Naples | Florida | 34102 | — |
| Clinical Trial Site | Orlando | Florida | 32801 | — |
| Clinical Trial Site | Acworth | Georgia | 30101 | — |
| Clinical Trial Site | Columbus | Georgia | 31904 | — |
| Clinical Trial Site | Fayetteville | Georgia | 30214 | — |
| Clinical Trial Site | Macon | Georgia | 31210 | — |
| Clinical Trial Site | Champaign | Illinois | 61822 | — |
| Clinical Trial Site | Valparaiso | Indiana | 46383 | — |
| Clinical Trial Site | West Des Moines | Iowa | 50266 | — |
| Clinical Trial Site | Lake Charles | Louisiana | 70601 | — |
| Clinical Trial Site | New Orleans | Louisiana | 70124 | — |
| Clinical Trial Site | Prairieville | Louisiana | 70769 | — |
| Clinical Trial Site | Baltimore | Maryland | 21229 | — |
| Clinical Trial Site | Jackson | Mississippi | 39209 | — |
| Clinical Trial Site | Jefferson City | Missouri | 65109 | — |
| Clinical Trial Site | Las Vegas | Nevada | 89119 | — |
| Clinical Trial Site | New York | New York | 10036 | — |
| Clinical Trial Site | The Bronx | New York | 10456 | — |
| Clinical Trial Site | Greensboro | North Carolina | 27408 | — |
| Clinical Trial Site | Greensboro | North Carolina | 27410 | — |
| Clinical Trial Site | Medford | Oregon | 97504 | — |
| Clinical Trial Site | Greenville | South Carolina | 29607 | — |
| Clinical Trial Site | Memphis | Tennessee | 38119 | — |
| Clinical Trial Site | Cedar Park | Texas | 78613 | — |
| Clinical Trial Site | Houston | Texas | 77074 | — |
| Clinical Trial Site | Houston | Texas | 77081 | — |
| Clinical Trial Site | Magnolia | Texas | 77355 | — |
| Clinical Trial Site | Pearland | Texas | 77584 | — |
| Clinical Trial Site | San Antonio | Texas | 78229 | — |
| Clinical Trial Site | Stephenville | Texas | 76401 | — |
| Clinical Trial Site | Tomball | Texas | 77375 | — |
| Clinical Trial Site | Waco | Texas | 76708 | — |
| Clinical Trial Site | Burke | Virginia | 22015 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04936035, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 23, 2025 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04936035 live on ClinicalTrials.gov.