A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity.
Public ClinicalTrials.gov record NCT04936542. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport®) in Comparison With OnabotulinumtoxinA (Botox®) When Treating Adults With Upper Limb Spasticity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each product.
Study identification
- NCT ID
- NCT04936542
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 464 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 23, 2021 (Actual)
- Primary completion
- Aug 26, 2025 (Actual)
- Completion
- Aug 26, 2025 (Actual)
- Last update posted
- Jul 9, 2026
2021 – 2025
United States locations
- U.S. sites
- 54
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 25233 | — |
| HonorHealth Scottsdale Osborn Medical Center | Scottsdale | Arizona | 85251 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| The University of Arizona | Tucson | Arizona | 85724 | — |
| Rancho Los Amigos National Rehabilitation Center (RLANRC) - Neurology | Downey | California | 90242 | — |
| Parkinson's & Movement Disorders Institute | Fountain Valley | California | 92708 | — |
| Neuro-Pain Medical Center | Fresno | California | 93710 | — |
| Loma Linda University Health Care | Loma Linda | California | 92350 | — |
| Southland Neurologic Institute | Long Beach | California | 90808 | — |
| University of California Los Angeles | Los Angeles | California | 90095 | — |
| Hasbani And Hasbani Medical Group | New Haven | Connecticut | 06511 | — |
| Ki Health Partners LLC D/B/A New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| First Choice Neurology | Boca Raton | Florida | 33428 | — |
| James A Haley Veterans Hospital | Tampa | Florida | 33612 | — |
| University of South Florida Health-Morsani Center for Advanced Healthcare | Tampa | Florida | 33612 | — |
| Emory University of School of Medicine | Atlanta | Georgia | 30322 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Shirley Ryan Ability Lab | Chicago | Illinois | 60611-3167 | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | 46804 | — |
| Kansas City Bone and Joint Clinic, P.A. (KCBJ) - Overland Pa | Overland Park | Kansas | 66211-1358 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| LSU Healthcare network | New Orleans | Louisiana | 70112 | — |
| UMass Memorial Medical Center - University Campus | Worcester | Massachusetts | 01655 | — |
| William Beaumont Hospital | Dearborn | Michigan | 48124 | — |
| Medical Rehabilitation Group, PC | Grand Blanc | Michigan | 48439 | — |
| Mary Free Bed Rehabilitation Hospital | Grand Rapids | Michigan | 49503 | — |
| Beaumont Hospital, Grosse Pointe | Grosse Pointe | Michigan | 48230 | — |
| Michigan Center of Medical Research | Grosse Pointe | Michigan | 48334 | — |
| Rusk Rehabilitation Center | Columbia | Missouri | 65203-3248 | — |
| Wr-Crcn, Llc | Las Vegas | Nevada | 89106 | — |
| Cooper University Health Care | Cherry Hill | New Jersey | 08003 | — |
| New York University | New York | New York | 10016 | — |
| Weill Cornell Medicine Clinical and Translational Science Center | New York | New York | 10065 | — |
| North Suffolk Neurology | Port Jefferson | New York | 11725 | — |
| Mayo Clinic | Rochester | New York | 55905 | — |
| Sunnyview Rehabilitation Hospital | Schenectady | New York | 12308 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Cleveland Clinic - Neurological Institute | Cleveland | Ohio | 44195 | — |
| MossRehab - Einstein Medical Center | Elkins Park | Pennsylvania | 20010 | — |
| Penn State Health Physical Medicine and Rehabilitation - Neurology | Hershey | Pennsylvania | 17033 | — |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | Pennsylvania | 15213 | — |
| Aether Medicine | Wayne | Pennsylvania | 19087 | — |
| Siskin Hospital for Rehabilitation - Neurology | Chattanooga | Tennessee | 37403 | — |
| The Vanderbilt Clinic | Nashville | Tennessee | 37232 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| TIRR Memorial Hermann Research Center | Houston | Texas | 77030 | — |
| UT Health San Antonio | San Antonio | Texas | 78229 | — |
| Texas Institute for Neurological Disorders | Sherman | Texas | 75093 | — |
| University of Utah School of Medicine | Salt Lake City | Utah | 84132 | — |
| Carilion Clinic Institute of Orthopaedics and Neurosciences | Roanoke | Virginia | 24016 | — |
| MedStar National Rehabilitation Network | Columbia | Washington | 20010 | — |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | — |
| Medical College of Wisconsin - Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04936542, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 9, 2026 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04936542 live on ClinicalTrials.gov.