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Completed Phase 3 Interventional Results available

A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

ClinicalTrials.gov ID: NCT04938427

Public ClinicalTrials.gov record NCT04938427. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 8:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Soticlestat as Adjunctive Therapy in Pediatric and Adult Subjects With Lennox-Gastaut Syndrome (LGS)

Study identification

NCT ID
NCT04938427
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Takeda
Industry
Enrollment
270 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Soticlestat Drug

Drug

Eligibility (public fields only)

Age range
2 Years to 55 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 7, 2021
Primary completion
Jan 24, 2024
Completion
Jan 24, 2024
Last update posted
Aug 20, 2024

2021 – 2024

United States locations

U.S. sites
24
U.S. states
16
U.S. cities
20
Facility City State ZIP Site status
Phoenix Childrens Hospital Phoenix Arizona 85016
Center For Neurosciences Tucson Arizona 85718
David Geffen School of Medicine at UCLA Los Angeles California 90095
University of California Benioff Children's Hospital San Francisco California 94143
Children's Hospital Colorado. Denver Colorado 80218
Pediatric Neurology PA Winter Park Florida 32789
Clinical Integrative Research Center of Atlanta Atlanta Georgia 30328
University of Iowa Hospitals & Clinics - (CRS) Iowa City Iowa 52242
Midatlantic Epilepsy and Sleep Center Bethesda Maryland 20817
Minnesota Epilepsy Group PA Roseville Minnesota 55113
Institute of Neurology and Neurosurgery at Saint Barnabas, LLC Livingston New Jersey 07039
Premier Healthcare Inc. New York New York 10001
NYU Comprehensive Epilepsy Center New York New York 10016
Northwell Health Physician Partners - Neurology at Lenox Hill New York New York 10075
Oregon Health and Science University Portland Oregon 97239
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
Thomas Jefferson University Philadelphia Pennsylvania 19107
St. Christopher's Hospital for Children Philadelphia Pennsylvania 19134
WellSpan Oncology Research York Pennsylvania 17403
Medical University of South Carolina Children Hospital - PIN Charleston South Carolina 29425
Cook Children's Medical Center - Jane and John Justin Neurosciences Center Fort Worth Texas 76104
University of Utah - Primary Children's Hospital - PPDS Salt Lake City Utah 84113
Seattle Children's Hospital Seattle Washington 98105
MultiCare Institute for Research & Innovation (Tacoma) Tacoma Washington 98402

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 74 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04938427, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 20, 2024 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04938427 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →